Research

Research

Our mission at MSOM is to prepare physicians who are professionally accomplished, socially responsible, and community-oriented. Our research foci mirror these goals in that MSOM research starts in our own community to benefit the greater good.

Demonstrating our commitment to this mission and focus, we have instituted a novel and rigorous four-semester research course. Research and scholarly activities start in the first semester, and students will complete their initial research project by the end of their second year. The goal for MSOM students is to develop research that addresses health issues and disparities faced in our Western Maryland community and beyond, while also providing learners with a thorough understanding of high-quality research practices. Student research projects will focus on health issues faced our community and beyond, and those approaches may include clinical, biomedical, population health, health equity, or other types of research.

During these first two pre-clinical years, as part of this four-semester research course, students will work in groups with a faculty mentor to design, develop, implement, complete, and disseminate a research project. Students will build a strong knowledge foundation in research methods and an understanding of research statistics during the first part of the first semester. Following that, mentors and student groups will be selected. Students are supported heavily throughout the research process and will have weekly time within the curriculum to meet with their mentors as well as designated research time each week. MSOM resources, such as the Meritus Health Institutional Review Board (IRB), data support, medical librarians, and other research mentorship will be available for MSOM students. Students will present their work at the annual Meritus Scholar-Con and may also present at regional or national conferences or publish their research in a peer-reviewed journal.

MSOM students may also have the option to participate in research with faculty, preceptors, and/or residents during their clinical rotations in third and fourth year.

Msom Research 032825

Vasauskas

Audrey Vasauskas, Ph.D.

Associate Dean of Research 

Dr. Vasauskas received her BS in Biology from Mount Saint Mary’s University in Maryland and her PhD from the University of South Alabama College of Medicine (departments of Pharmacology and Comparative Medicine). She completed a four-year postdoctoral fellowship in the Center for Lung Biology at the University of South Alabama, and during this time received an F32 Ruth Kirschstein National Research Service Award by the National Institutes of Health to fund her work in pulmonary endothelial physiology. Her research has also been funded by the American Heart Association (AHA), the National Heart, Lung, and Blood Institute (NHLBI), the American Medical Association (AMA), and the Network of the National Library of Medicine (NNLM). In addition to her pulmonary biology research, Dr. Vasauskas also has interest in the effects of proactive self-care and stress reduction, including nutrition, osteopathic manipulative treatment (OMT), yoga, and exercise on disease prevention and reversal. This interest is expanding from investigating effects of wellness proactivity on not only the individual, but also entire communities.

Dr. Vasauskas has been conducting research and teaching physiology, biology, and medical science-related courses for over 15 years and has mentored undergraduate, graduate, and medical students in both industry and academia. Prior to her career in academia, she spent several years in the biotechnology industry, where she served as project leader for oncology diagnostic development.

Dr. Vasauskas has experience in developing and growing institutional research programs, overseeing multiple research projects, instituting and ensuring research compliance, maintaining and accreditation reports, and directing student and faculty research.  She most recently served as the Associate Dean for Research and Scholarly Activity and Associate Professor of Physiology at the Baptist University College of Osteopathic Medicine. Prior to that, she served as the Director of Research and Grant Development and Associate Professor of Physiology at the Alabama College of Osteopathic Medicine. She is also a registered yoga teacher and has been leading yoga classes since 2006.

Faculty Research Interest and Scholar Work Summary

  • Atluri, Venkata

    Research Interests:

    • Role of Inflammasome-mediated neuroinflammation in the neuropathogenesis of HIV-infection and Alzheimer’s Disease.
    • Use of CRISPR/Cas9 gene-editing technology targeting latent HIV infection in the brain.
    • Use of nanotechnology-based drug delivery approaches targeting HIV infection in the brain and Alzheimer’s disease.

    Scholarly Work:

    Publications:

    ·        Nagesh Kolishetti, Arti Vashist, Adriana Yndart Arias, Venkata Atluri, Shanta Dhar, and Madhavan Nair (2022). Recent advances, status, and opportunities of magneto-electric nanocarriers for biomedical applications. Molecular Aspects of Medicine, 83; 101046. https://doi.org/10.1016/j.mam.2021.101046

    ·        Vashist A, Atluri V, Raymond A, Kaushik A, Parira T, Huang Z, Durygin A, Tomitaka A, Nikkhah-Moshaie R, Vashist A, Agudelo M, Chand H, Saytashev I, Ramella-Roman JC and Nair M (2020). Development of Multifunctional Biopolymeric Auto-Fluorescent Micro and Nanogels as a Platform for Biomedical Applications. Front. Bioeng. Biotechnol. 8:315. doi: 10.3389/fbioe.2020.00315.

    ·        Atluri VSR, Tiwari S, Rodriguez M, Kaushik A, Yndart A, Kolishetti N, Yatham M, and Nair M (2020). Inhibition of Amyloid-Beta Production, Associated Neuroinflammation, and Histone Deacetylase 2-Mediated Epigenetic Modifications Prevent Neuropathology in Alzheimer’s Disease in vitro Model. Frontiers in Aging Neuroscience, 11:342. doi: 10.3389/fnagi.2019.00342

    ·        Sneham Tiwari, Venkata Atluri, Ajeet Kaushik, Adriana Yndart, Madhavan Nair. 2019.  Alzheimer’s disease: Pathogenesis, Diagnostics, and Therapeutics. International Journal of Nanomedicine, 2019: 5541-5554.

    ·        Ajeet Kaushik, Adriana Yndart, Venkata Atluri, Sneham Tiwari, Asahi Tomitaka, Purnima Gupta, Rahul Dev Jayant, David Alvarez‑Carbonell, Kamel Khalili, Madhavan Nair. 2019.  Magnetically guided non-invasive CRISPR-Cas9/gRNA delivery across the blood-brain barrier to eradicate latent HIV-1 infection. Scientific Reports 9, 3928.

    ·        Sneham  Tiwari,   Venkata Subba Rao Atluri, Adriana  Yndart  Arias, Rahul Dev Jayant, Ajeet Kaushik, Jonathan D Geiger, and Madhavan N Nair. 2018. Withaferin A suppresses Beta-amyloid in APP expressing cells: Studies for Tat and Cocaine associated neurological dysfunctions. Frontiers in Aging Neuroscience 10.

    ·        Jayant, R.D., Tiwari, S., Atluri, V., Kaushik, A., Tomitaka, A., Yndart, A., Colon-Perez, L., Febo, M., and Nair, M. 2018. Multifunctional Nanotherapeutics for the Treatment of neuroAIDS in Drug Abusers. Scientific Reports 8, 12991.

    ·        Upal Roy, Vadym Drozd, Andriy  Durygin,  Jesse  Rodr´ıguez,  Paul  Barber, Venkata Atluri, Xiaohua Liu, Thomas G Voss, Surendra Saxena, and Madhavan Nair. 2018. Characterization of Nanodiamond-based anti- HIV drug Delivery to the Brain. Scientific Reports 8; 1603. doi: 10.1038/s41598-017-16703-9.

    ·        Thangavel Samikkannu, Carmen T. Mulet, Venkata Atluri, Marisela Agudelo, Rhonda Rosenberg, Jessy G. Devieux, and Madhavan Nair. 2018. Oxidative Stress in HIV infection and alcohol use: Role of redox signals in the modulation of lipid rafts and ABC-transporters. Antioxidants and Redox Signaling, 28(4): 324-337.

    ·        Venkata S R Atluri*., Rahul Dev Jayant*., Sneham Tiwari., Sudheesh Pilakka Kanthikeel., Ajeet Kaushik., Adriana Yndart and Madhavan Nair. 2017. Novel nanoformulation to mitigate co-effects of drugs of abuse and HIV-1 infection: Towards the treatment of NeuroAIDS. J Neurovirol. 2017 Jul 31. doi: 10.1007/s13365-017-0538-8. *Equal First Author Contribution.

    ·        Vidya Sagar., Sudheesh Pilakka Kanthikeel., Paola C. Martinez., V S R Atluri, and Madhavan Nair. 2017. Common gene-network signature of different neurological disorders and their potential implications to neuroAIDS. PLoS One. 2017 Aug 8; 12(8): e0181642. doi: 10.1371/journal.pone.0181642.

    ·        Ajeet Kaushik, Roozbeh Nikkhah-Moshaie,  Raju  Sinha, Vinay Bhardwaj, Venkata Atluri, Rahul Jayant, Adriana  Yndart,  Babak  Kateb, Nezih Pala, and Madhavan Nair.  2017.  Investigation of ac-magnetic field stimulated nano electroporation of magneto-electric nano-drug-carrier inside CNS cells. Scientific Reports,7: 5663. doi:10.1038/srep45663.

    ·        Venkata SR Atluri, Rahul Dev Jayant, Sudheesh  Pilakka  Kanthikeel,  Gabriella  Garcia,  Samikkannu Thangavel, Adriana  Yndart,  Ajeet  Kaushik, and Madhavan Nair.  2016.  Development of TIMP1 magnetic nanoformulation for the regulation of synaptic plasticity      HIV-1   infection.   International   Journal of Nanomedicine. doi: 10.2147/IJN.S108329.

    ·        Samikkannu Thangavel., Venkata Atluri., Madhavan Nair. 2016. HIV and Cocaine Impact Glial Metabolism: Energy Sensor AMP-activated protein kinase Role in Mitochondrial Biogenesis and Epigenetic Remodeling. Scientific Reports, 6: 31784. doi: 10.1038/srep31784.

    ·        Ajeet Kaushik, Venkata Atluri, Phani Kiran  Vabbina,   Pratikkumar   Shah, Rahul Dev Jayant, Adriana Yandart, Madhavan Nair. 2016. Electrochemical monitoring-on-chip (E-MoC) of HIV infection in the presence of cocaine and therapeutics. Biosensors and Bioelectronics, 86: 426-431. doi: 10.1016/j.bios.2016.06.086.

    ·        Sagar, V., Atluri, V.S.R., Kami, A., Shah, P., Nagasetti, A., Pilakka-Kanthikeel, S., El-Hage, N., McGoron, A., Takemura, Y. & Nair, M. 2016. Coupling of transient near-infrared photonic with magnetic nanoparticle for potential dissipation-free biomedical application in the brain. Scientific Reports, 6: 29792. doi:10.1038/srep29792.

    ·        Venkata S Atluri, Sudheesh   Pilakka-Kanthikeel,   Gabriella   Garcia, Rahul   Dev   Jayant, Vidya   Sagar, Samikkannu  Thangavel, Adriana  Yndart,  Madhavan  Nair.  2016.  Effect of Cocaine on HIV Infection and Inflammasome Gene Expression Profile in HIV Infected Macrophages.  Scientific Reports, 6: 27864. doi:10.1038/srep27864.

    ·        Marisela Agudelo, Gloria Figueroa, Adriana Yndart, Karla Munoz, Venkata Atluri, Samikkannu Thangavel, Madhavan P.  Nair.  2016.  Profile of Class I Histone Deacetylases (HDAC) by Human Dendritic Cells after Alcohol Consumption and in vitro Alcohol Treatment and their Implication in Oxidative Stress:  Role of HDAC Inhibitors     Trichostatin     A     and     Mocetinostat.     PLoS     ONE     11(6):     e0156421.     doi:10.1371/journal.pone.0156421.

    ·        Atluri, V.S.R*., Sagar, V*., Pilakka-Kanthikeel, S., & Nair, M. 2016. Magnetic nanotherapeutics for synaptic plasticity dysregulations during neuroAIDS and drug abuse. Molecular Brain, 9:57. DOI: 10.1186/s13041-016-0236-0. *Equal First Author Contribution.

    ·        Rahul Dev Jayant, Daniela Sosa, Ajeet Kaushik, Venkata Atluri, Arti Vashist, Asahi Tomitaka,  Madhavan Nair. 2016. Current status of non-viral gene therapy for CNS disorders. Expert Opinion on Drug Delivery. DOI:10.1080/17425247.2016.1188802.

    ·        Ajeet Kaushik, Rahul D. Jayant, Roozbeh Nikkhah-Moshaie, Vinay Bhardwaj, Upal Roy, Zaohua Huang, Ariel Ruiz, Adriana Yndart, Venkata Atluri, Nazira El-Hage, Kamel Khalili, Madhavan Nair. 2016. Magnetically guided central nervous system delivery and toxicity evaluation of magneto-electric nanocarriers. Scientific Reports. 6:25309; DOI: 10.1038/srep25309.

    ·        Venkata Subba Rao Atluri. 2016. Editorial:  HIV and illicit drugs of abuse. Frontiers in Microbiology. 7:221. doi: 10.3389/fmicb.2016.00221.

    ·        Venkata Subba Rao Atluri*, Kesava Rao Venkata Kurapati*, Samikkannu  Thangavel, Gabriella Garcia, Madhavan Nair.  2016.  Natural Products as Anti-HIV Agents and Role in HIV-Associated Neurocognitive Disorders (HAND): A Brief Overview. Frontiers in Microbiology, 6: 01444. doi:  10.3389/fmicb.2015.01444. *Equal First Author Contribution.

    ·        Marisela Agudelo., Gloria Figueroa., Adriana Yndart., Gianna Casteleiro., Karla Muñoz., Thangavel Samikkannu., Venkata Subba Rao Atluri and Madhavan P. Nair. 2015. Alcohol and cannabinoids differentially affect HIV infection and the function of human monocyte-derived dendritic cells (MDDC). Frontiers in Microbiology, 6:1452. doi: 10.3389/fmicb.2015.01452.

    ·        Venkata Atluri, Melissa Hidalgo,  Samikkannu Thangavel, Kesava Rao Kurapati, Madhavan Nair. 2015. Synaptic plasticity and cognitive disorders in neurotropic viral infections. Neural Plasticity, Article ID: 138979, http://dx.doi.org/10.1155/2015/138979.

    ·        Upal Roy, Hong Ding, Sudheesh  Pilakka  Kanthikeel,  Andrea  Raymond, Venkata Atluri, Adriana  Yndart, Madhavan Nair. 2015. Preparation and characterization of anti-HIV nano-drug targeted to microfold cells of gut-associated lymphoid tissue. International Journal of Nanomedicine, 10: 5819-5835. PMID: 26425084.

    ·        Venkateswara Reddy Gogulamudi, Mohan Lal Dubey, Deepak Kaul, Venkata Subba Rao Atluri, Rakesh Sehgal.  2015. Downregulation of the host tryptophan-aspartate-containing coat (TACO) gene restricts the entry and survival of Leishmania donovani in the human macrophage model. Frontiers in Microbiology, 6:946. doi: 10.3389/fmicb.2015.00946.

    ·        Upal Roy, Venkata Atluri, Marisela Agudelo, Madhavan Nair.  2015.  DJ1 Expression Downregulates in Neuroblastoma Cells (SK-N-MC) Chronically Exposed to HIV-1 and Cocaine. Frontiers in Microbiology, 6: 749. doi: 10.3389/fmicb.2015.00749. PMID: 26284039.

    ·        Adriana Yndart, Ajeet Kaushik, Marisela Agudelo, Andrea Raymond, Venkata Atluri, Shailendra Saxena, and Mahdavan Nair. 2015. Investigation of Neuropathogenesis in HIV-1 Clade B and C Infection Associated with IL-33 and ST2 Regulation. ACS Chemical Neuroscience. 2015 Sep 16;6(9):1600-12. PMID: 26110635.

    ·        Samikkannu T, Ranjith D, Rao KVK, Atluri VSR, Pimentel E, El-Hage N, Nair MPN. 2015. HIV-1 gp120 and morphine-induced oxidative stress: role in cell cycle regulation. Front. Microbiol. 6:614. doi: 10.3389/fmicb.2015.00614. PMID: 26157430.

    ·        Sagar Vidya, Pilakka-Kanthikeel   S, Atluri   VSR, Ding   H, Priestap H, Nair   M.P.    2015. Therapeutical Neurotargeting via   Magnetic   Nanocarrier:   Implications to   Opiate-Induced   Neuropathogenesis and NeuroAIDS. Journal of Biomedical Nanotechnology, 11: 1722-1733. PMID: 26502636.

    ·        Samikkannu Thangavel, Kesava   Rao Kurapati, Abdul Ajees   Abdul   Salam, Venkata   Atluri, Elena Kaftanovskaya, Marisela Agudelo, Suray Perez, Andrea Raymond, Hong Ding, Madhavan Nair. 2015. HIV Subtypes B and C gp120 and Methamphetamine Interaction: Role of Dopaminergic System Implicates Differential Neuronal Toxicity. Scientific Reports. 5. Article number: 11130 doi:10.1038/srep11130. PMID: 26057350.

    ·        Venkata Atluri, Melissa Hidalgo, Samikkannu Thangavel, Kesava Rao Kurapati, Rahul Jayant, Vidya Sagar, Madhavan Nair.  2015.  Effect of human immunodeficiency virus on blood-brain barrier integrity and function:  an update.  Frontiers in Cellular Neuroscience, 9:212.  doi:  10.3389/fncel.2015.00212.  PMID: 26113810.

    ·        Sudheesh PK, Andria Raymond, Venkata Subba Rao Atluri; Vidya Sagar, Shailendra Saxena, Patricia Diaz, Semithe Chevelon, Michael Concepcion, Madhavan Nair. 2015. Sterile alpha motif and histidine/aspartic acid domain-containing protein 1 (SAMHD1)-facilitated HIV restriction in astrocytes is regulated by miRNA- 181a. Journal of Neuroinflammation 2015, 12:66. PMID: 25890101.

    ·        Venkata Atluri*,   Melissa   Hidalgo*,   Madhavan   Nair. 2015. Drugs of abuse in HIV infection and neurotoxicity. Frontiers in Microbiology, 6: 217. PMID: 25852673. *Equal First Author Contribution.

    ·        Rahul Dev Jayant, Venkata Atluri, Marisela Agudelo, Vidya Sagar, Ajeet Kaushik, Madhavan Nair.  2015. Sustained Release NanoART Formulation for the Treatment of NeuroAIDSInternational Journal of Nanomedicine, 10: 1077-1093. PMID: 25709433.

    ·        Ajeet Kaushik, Adriana Yndrt, Rahul Dev Jayant, Vidya Sagar, Venkata Atluri, Shekhar Bhansali, Madhavan Nair. 2015. Electrochemical sensing method for point-of-care cortisol detection in HIV-infected patients. International Journal of Nanomedicine, 10:  677-685.  PMID: 25632229.

    ·        Samikkannu Thangavel, Venkata Atluri, Adriana Yndart, Kesava Rao Venkata Kurapati, Carmen T Mulet, Rahul Dev Jayant, Madhavan Nair. 2014. HIV-1 Subtypes B and C Tat Differentially Impact Synaptic Plasticity Expression and Implicates HIV-Associated Neurocognitive Disorder. Current HIV Research, 12(6), 397-405. PMID: 25613138.

    ·        Kesava Rao Venkata Kurapati, Thangavel Samikkannu, Venkata Subba Rao Atluri, Elena  Kaftanovskaya, Adriana  Yndart, Madhavan P. N. Nair. 2014. β-Amyloid1-42, HIV-1Ba-L (Clade B) Infection and Drugs of Abuse Induced Degeneration in Human Neuronal Cells and Protective Effects of Ashwagandha (Withania somnifera) and Its Constituent Withanolide A. PLoS ONE9(11): e112818. doi: 10.1371/journal.pone.0112818. PMID: 25415340.

    ·        Venkata Subba Rao Atluri, Kesava Rao Venkata Kurapati, Thangavel Samikkannu and Madhavan P.N. Nair. 2014. Biomarkers of HIV Associated Neurocognitive Disorders. JSM Biomarkers; 1(1): 1002.

    ·        Venkata Subba Rao Atluri, Venkateswara Reddy  Gogulamudi,  Pratibha  Singhi, Niranjan Khandelwal, Lakshmana Swamy  Parasa,  Nancy  Malla.  2014.  Pediatric neurocysticercosis:  usefulness of antibody response in cytocidal treatment follow-up.  BioMed Research International.  Volume 2014, Article ID # 904046. http://dx.doi.org/10.1155/2014/904046. PMID: 25215297.

    ·        Atluri, V.S.R., Pilakka-Kanthikeel, S., Samikkannu, T. et al. Vorinostat positively regulates synaptic plasticity genes expression and spine density in HIV infected neurons: role of nicotine in the progression of HIV-associated neurocognitive disorder. Mol Brain 7, 37 (2014). https://doi.org/10.1186/1756-6606-7-37.

    ·        Samikkannu  T, Rao KV,  Pilakka  Kanthikeel  S, Venkata SR Atluri, Agudelo M, Roy U, Nair MP.  2014. Immunoneuropathogenesis of HIV-1 clades B and C: Role of redox expression and thiol modification. Free Radic Biol Med. 2014; 69:136-44. PMID: 24480751.

    ·        Hong Ding, Vidya Sagar, Marisela Agudelo, Sudheesh  Pilakka-Kanthikeel, Venkata Subba Rao Atluri, Andrea Raymond, Thangavel  Samikkannu and Madhavan P Nair.  2014.  Enhanced blood-brain barrier transmigration using a novel transferrin-embedded fluorescent magneto-liposome nanoformulation. Nanotechnology 25; 055101, doi:10.1088/0957-4484/25/5/055101. PMID: 24406534.

    ·        Venkata Subba Rao Atluri, Thangavel  Samikkannu,  Kesava Rao Venkata Kurapati, Madhavan PN Nair. 2014. Commentary of Drugs of Abuse and HIV Infection in South Florida, USA.  Austin Journal of Drug Abuse and Addiction. 05/2014; 1(1):3.

    ·        Kurapati, V.K.R, Samikkannu T, Atluri, V.S.R, Nair, M.P.N. 2014. Cell Cycle Checkpoints and Pathogenesis of HIV-1 Infection: A Brief Overview. Journal of basic and clinical physiology and pharmacology. July 19, 2014, DOI: 10.1515/jbcpp-2014-0018. PMID: 25046311.

    ·        Rakesh Guduru, Ping Liang, Carolyn D.  Runowicz, Madhavan Nair, Venkata Atluri, Sakhrat Khizroev. 2013. Magneto-electric Nanoparticles to Enable Field-controlled High-Specificity Drug Delivery to Eradicate Ovarian Cancer Cells. Scientific Reports. 2013/10/16/online. doi: 10.1038/srep02953.

    ·        Kurapati KRV, Atluri VSR, Samikkannu T, Nair MPN. 2013. Ashwagandha (Withania somnifera) Reverses β- Amyloid1-42 Induced Toxicity in Human Neuronal Cells:  Implications in HIV-Associated Neurocognitive Disorders (HAND). PLoS ONE 8(10): e77624. doi: 10.1371/journal.pone.0077624.

    ·        Venkata Subba Rao Atluri, Sudheesh P.  Kanthikeel, Pichili VB Reddy, Adriana Yndart, Madhavan Nair. 2013. Human Synaptic Plasticity gene expression profile and dendritic spine density changes in HIV-infected human neuronal cells:  Role in HIV-associated neurocognitive disorders.  PLoS ONE 8(4):  e61399. doi:10.1371/journal.pone.0061399.

    ·        Sudheesh PK; Venkata Subba Rao Atluri, Vidya Sagar, Madhavan Nair.  2013. Targeted Brain Derived Neurotropic Factors (BDNF) Delivery across the Blood-Brain Barrier for Neuro-Protection Using Magnetic Nano Carriers: An In-Vitro Study. PLoS ONE 8(4): e62241. doi: 10.1371/journal.pone.0062241.

    ·        Reddy PV, Agudelo M, Atluri VS, Nair MP. Inhibition of nuclear factor erythroid 2-related factor 2 exacerbates HIV-1 gp120-induced oxidative and inflammatory response: role in HIV associated neurocognitive disorder. Neurochem Res. 2012;37(8):1697-1706. doi:10.1007/s11064-012-0779-0

    ·        Rita  Mukhopadhyay., Goutam   Mandal., Venkata Subba Rao Atluri.,  Katherine   Figarella., Nestor L. Uzcategui., Yao Zhou., Eric Beitz., A. Abdul Ajees and Hiranmoy Bhattacharjee. 2011. The role of alanine 163 in solute permeability of Leishmania major aquaglyceroporin LmAQP1. Molecular and Biochemical Parasitology, 175(1): 83-90.

    ·        Atluri, V.S.R., Singhi, P., Khandelwal, N., Malla, N. 2011. 2D-PAGE analysis of Taenia solium metacestode 10- 30 kDa antigens for the serodiagnosis of neurocysticercosis in children. Acta Tropica, 2011; 118(2): 165- 169.

    ·        Sehgal R., Gogulamudi V.  Reddy., Jaco J.  Verweij., Atluri V.  Subba Rao.  2010.  Prevalence of intestinal parasitic infections among school children and pregnant women in a low socio-economic area, Chandigarh, North India. Reviews in Infection, 1(2): 100-103.

    ·        Lakshmana swamy Parasa., Cyril Arun kumar., Sirisha Para., Venkata Subba Rao Atluri, K. Santhisree, P. Raja Kumar and C. Rattiah Setty.  2010.  Epidemiological survey of methicillin-resistant Staphylococcus aureus in the community and hospital, Gannavaram, Andhra Pradesh, South India. Reviews in Infection, 1(2): 117-123.

    ·        Atluri, V.S.R., Singhi, P., Khandelwal, N., Malla, N. 2009. Evaluation of excretory-secretory and 10-30 kDa antigens of T. solium Cysticerci by EITB assay for the diagnosis of neurocysticercosis. Parasite Immunology, 31(3): 151-5.

    ·        Atluri, V.S.R., Singhi, P., Khandelwal, N., Malla, N. 2009. Neurocysticercosis immunodiagnosis using Taenia solium Cysticerci crude soluble extract, excretory-secretory and lower molecular mass antigens in serum and urine samples of Indian children. Acta Trop., 110(1):22-7.

     

    Book chapters:

    ·        Arti Vashist, Nagesh Kolishetti, Adriana Yndart Arias, Andrea D. Raymond, Atul Vashist, Sukanya Bhunia, Deborah Brooks, Venkata Atluri, and Madhavan Nair. 2024.  Chapter 10: Recent updates on the emerging role of vegetable oils in the development of hydrogel technology for biomedical applications. Vegetable Oil-Based Polymers and Their Surface Applications. Publisher: Elsevier Inc. ISBN 978-0-12-822189-1. https://doi.org/10.1016/B978-0-12-822189-1.00014-3.

    ·        Venkata Atluri, Ravi Doddapaneni, Eliset Perez.  2017.  Personalized Therapeutics:  First Take-Home Messages. Book Title: Advances in Personalized Nanotherapeutics. ISBN:978-3-319-63632-0. Publisher: Springer, Cham, doi: 10.1007/978-3-319-63633-7_2.

     

    Conference Presentations:

    ·        Sydney Sands, Vincent Tran, Hayden Evans, Elizabeth Sarkisian, Deirdre Kokasko, Rickey Shah, Ram Batta, Shelbi Salinas, Leah Kramer, Julie McGroarty, and Venkata Atluri. Role of NLRP3-Inflammasome-Mediated Inflammatory Response Induced by Amyloid Precursor Protein (APP695) and its Swedish Mutant in the Development of Alzheimer’s Disease. Noorda COM Research Symposium, 2024.

    ·        Braydon Black, Nestor Cruz1, Bryan Jimenez, Trevor Moore, Scott Baker, and Venkata Atluri. Inflammasome Genes Expression in Alzheimer’s Disease Cell Culture Models and its Role in the Development of AD Pathology. Noorda COM Research Symposium, 2024.

    ·        Sydney Sands, Bryan Jimenez, Vincent Tran, Hayden Evans, Trevor Moore, Braydon Black, Nestor Cruz, Elizabeth Sarkisian, and Venkata Atluri. 2024. Role of Amyloid Precursor Protein (APP695) and its Swedish Mutant in Inducing Inflammasome-Mediated Inflammatory Response in the Brain. Roseman University Research Symposium 2024, South Jordan, Utah.

    ·        Venkata Atluri, Adriana Yndart, Nagesh Kolishetti, Arti Vashist, Alexandros Makriyannis, and Madhavan Nair. 2023. Anti-HIV and Anti-inflammasome Activity of a Novel Chiral Potent Endocannabinoid Ligand (R)- N-(1-Methyl-2-hydroxyethyl)-13-(S)-methyl-arachidonamide (AMG315). 19th International Symposium on NeuroVirology, Montreal, Quebec, Canada.

    ·        Devin Pfister, Maria Avakova, Brooke Johnston, Joshua Hamm, Sean Donnelly, Sneham Tiwari, Prem Chapagain, Madhavan Nair, and Venkata Atluri. Therapeutic use of amyloid-beta and inflammasome-inhibitors to prevent the development of neuropathology in Alzheimer's disease. Roseman University Symposium, 2023.

    ·        Devin Pfister, Maria Avakova, Brooke Johnston, Joshua Hamm, Sean Donnelly, Sneham Tiwari, Prem Chapagain, Madhavan Nair, and Venkata Atluri. Therapeutic use of amyloid-beta and inflammasome-inhibitors to prevent the development of neuropathology in Alzheimer's disease. Noorda COM Research Symposium, 2023.

    ·        Sean Donnelly, Brooke Johnston, Devin Pfister, Victor M Jimenez, and Venkata S Atluri. Elimination of HIV-1 latency in the brain cells targeting HIV-1 Tat and LTR genes using a combination of CRISPR gene-editing and nanotechnology approaches. Noorda COM Research Symposium, 2022.

    ·        Maria Avakova, Joshua Hamm, Kota Ramana, and Venkata S Atluri. Immunotherapy and nanotechnology combinatory approach for the treatment of Alzheimer’s Disease. Noorda COM Research Symposium, 2022.

    ·        Kolishetti, N., Surnar, B., Shah, A., Ramirez-Jaime, R., Atluri, V., Arias, A. Y., Nair, M., and Dhar, S. “Combination therapy using brain accumulating polymeric nanoparticles for tackling HIV-infected brain reservoirs in drug abuse population” at TechConnect World 2021, in Washington DC October 18-20 2021.

    ·        Kolishetti, N.; Surnar, B.; Shah, A.; Kamran, M. Z.; Royden, R.; Atluri, V.; Arias, A. Y.; Nair, M., and Dhar, S. “A Combination therapy using brain accumulating polymeric nanoparticles for tackling HIV-infected brain reservoirs in drug abuse population” at the ACS Spring Meeting 2021, United States, April 5, - April 30, 2021 (2021), POLY-. (Research Presentation).

    ·        Ann Barral, Venkata Atluri, Sneham Tiwari, Melisa Rodriguez, Ajeet Kaushik, Adriana Yndart, Nagesh Kolishetti, Mohan Yatham, Madhavan Nair. Inhibition of Aβ production, associated neuroinflammation and HDAC2-mediated epigenetic modifications prevent neuropathology in Alzheimer’s disease. 6th Annual Personalized NanoMedicine Symposium - November 20th, 2019, Miami, FL.

    ·        Cardenas, Chabeli., Rodriguez, Melisa., Yatham, Puja., Miller, Nicole., Atluri, Venkata., Nair, Madhavan. Therapeutic Use of Withaferin A and INF4E in Alzheimer’s Disease.  F-STAR Summer Research Program Symposium, 2018, at FIU, Miami, FL.

    ·        Venkata Atluri, Sneham Tiwari, Melisa Rodriguez, Puja Yatham, Adriana Yndart, Ajeet Kaushik, Purnima Gupta, and Madhavan Nair.  Withaferin A and CRID3 inhibit neuropathology of Alzheimer’s disease:  A nanotechnology approach. 5th Annual Personalized NanoMedicine Symposium, November 1-2, 2018. Miami, FL.

    ·        Sneham Tiwari, Adriana  Yndart, Venkata Atluri, Rahul Dev Jayant, Ajeet Kaushik, Asahi  Tomitaka, Madhavan Nair. Withaferin A is a neuroprotective agent: Studies towards neurocognitive disorders. 24th Scientific Conference of the Society on Neuroimmune Pharmacology. April 10-14, 2018, Chicago, Illinois, USA.

    ·        Upal Roy, Vadym Drozd, Andriy Durygin, Jesse Rodriguez, Paul Barber, Venkata Atluri, Xiaohua Liu, Thomas G Voss, Jonathan C Abshier, Surendra Saxena, Madhavan Nair. Development of Nanodiamond-based anti-HIV drug delivery targeted to the Brain. 24th Scientific Conference of the Society on Neuroimmune Pharmacology. April 10-14, 2018, Chicago, Illinois, USA.

    ·        Venkata Subba Rao Atluri, Sudheesh Pilakka-Kanthikeel, Gabriella Garcia, Rahul Dev Jayant, Vidya Sagar, Thangavel Samikkannu, Adriana Yndart & Madhavan Nair. Inflammasome Gene Expression and their role in HIV and Cocaine-Induced Apoptosis. SNIP 23rd Scientific Conference, 2017, Philadelphia, USA.

    ·        Nikkhah-Moshaie, Roozbeh., Kaushik, A., Sinha, R., Bhardwaj, V., Atluri, V., Jayant, R.D., Yndart, A., Pala, N., Nair, M. Nanoelectroporation of magneto-electric nanoparticles as drug nano-carriers into the brain cells. SNIP 23rd Scientific Conference, 2017, Philadelphia, USA.

    ·        Sagar, VIDYA., Atluri, V.S.R., Tomitak,  A.,  Nagasetti,  A.,  Vashisit,  A.,  Pilakka-  Kanthikeel,  S., El-Hage, N., McGoron, A., Nair, M. NIR-stimuli sensitive ‘smart’ magnetic nanoagent for on demand drug delivery. SNIP 23rd Scientific Conference, 2017, Philadelphia, USA.

    ·        Thangavel, S., Atluri, VSR., Nair. Cocaine and HIV Upregulate Glycolytic Enzymes and Mitochondrial Biogenesis in Astrocytes. SNIP 23rd Scientific Conference, 2017, Philadelphia, USA.

    ·        Vashist, Arti., Kaushik, Ajeet., Atluri, Venkata., Nikkhah-Moshaie, Roozbeh., Tomitaka, Asahi., Sagar, Vidya., Nair, Madhavan.  Development of novel biopolymer based magnetic micro/nano hydrogels for targeted drug delivery and theranostic applications. SNIP 23rd Scientific Conference, 2017, Philadelphia, USA.

    ·        Venkata Subba Rao Atluri, Rahul Dev Jayant, Sudheesh Pilakka Kanthikeel, Gabriella Garcia, Samikkannu Thangavel, Adriana Yndart, Ajeet Kaushik. Development of Tissue Inhibitor of Metalloproteinase-1 (TIMP- 1) Magnetic  Nanoformulation for Regulation of Synaptic Plasticity in HIV-1 Infection. 9th Nanoflorida Symposium, Orlando.

    ·        Venkata Atluri, Rahul Dev Jayant, Gabriella Garcia, Sudheesh Pilakka-Kanthikeel, Samikkannu Thangavel, Adriana Yndart, Ajeet Kaushik, Madhavan P.N. Nair. Development of Tissue Inhibitor of Metalloproteinase- 1 (TIMP-1)   Magnetic   Nanoformulation   for   Regulation   of   Synaptic   Plasticity   in   HIV-1   Infection. International Journal of Nanomedicine. 3rd Personalized NanoMedicine Symposium, 2016, Miami, FL.

    ·        Venkata Atluri, Melisa Hidalgo, Oscar Hernandez, Sudheesh Pilakka Kanthikeel, Kesava Rao, Samikkannu Thangavel, Vidya Sagar, Rahul Jayant, Adriana Yndart, Andrea Raymond, Marisela Agudelo, Ajeet Kaushik, Madhavan P.N.  Nair.  Role of Vorinostat in Regulation of Synaptic Plasticity Genes Expression in Nicotine Co treated HIV Infected Neurons. 2nd Personalized NanoMedicine Symposium, 2015, Miami, FL.

    ·        Melissa Hidalgo, Venkata Atluri, Oscar Hernandez, Sudheesh Pilakka-Kanthikeel,   Madhavan   Nair. Dysregulation of synaptic plasticity in HIV infected Primary Neurons: Implication in HAND. 17th Annual Biomedical and Comparative Immunology symposium, 2015, at Miami, FL.

    ·        Atluri, VSR., Hernandez, O., Hidalgo, M., Kurapati, KRV., Thangavel, S.,  PilakkaKanthikeel,  S., Sagar, V., Yndart, A., Nair, M. Methamphetamine treatment and HIV-1 infection dysregulate Synaptic plasticity in SKNMC neuronal cells. 21st SNIP Conference, 2015 in Miami, FL, USA. J Neuroimmune Pharmacol (2015) 10(Suppl 2): S57–S112 DOI 10.1007/s11481-015-9596-y.

    ·        Jayant, R.D., Atluri, V., Agudelo, M., Kaushik, A., Nair, M. Sustained Release NanoART Formulation for the Treatment of NeuroAIDS. 21st SNIP Conference, 2015 in Miami, FL, USA. J Neuroimmune Pharmacol (2015) 10(Suppl 2): S57–S112 DOI 10.1007/s11481-015-9596-y.

    ·        Kauhsik, A., Jayant, RD., Roy, U., Huang, Z., Ruiz, A., Yndart,  A., Sagar, V., Atluri, V., Nikkhah, R., Bharadwaj, V., Nair, M. In vitro & In-vivo Cytotoxic Evaluation of Magneto-Electric Nanoparticles for the CNS   Delivery.  21st SNIP Conference, 2015   in Miami, FL, USA. J Neuroimmune  Pharmacol  (2015) 10(Suppl 2): S57–S112 DOI 10.1007/s11481-015-9596-y.

    ·        Kurapati, VKR., Ssmikkannu, T., Atluri, VSR., Yndart, A., Nair, MPN. β -Amyloid, HIV-1 Infection and Drugs of Abuse Induced Neurodegeneration and Protective Effects of Ashwagandha. 21st SNIP Conference, 2015 in Miami, FL, USA.  J Neuroimmune Pharmacol (2015) 10(Suppl 2): S57–S112 DOI 10.1007/s11481- 015-9596-y.

    ·        Pilakka-Kanthikeel,  S., Raymond, A., Atluri, VSR., Sagar, V., Nair, M. MicroRNA-155 regulates SAMHD1 facilitated HIV restriction in astrocyte. 21st SNIP Conference, 2015 in Miami, FL, USA. J Neuroimmune Pharmacol (2015) 10(Suppl 2): S57–S112 DOI 10.1007/s11481-015-9596-y.

    ·        Roy, U., DIng, H., Huang, Z., Kaushik, A., Jayant, R., Kanthikeel, S., Raymond, A., Sagar, V., Yndart- Arias, A., Atluri, V., Nair, M.P.  Characterization of on Demand Delivery of Fluorescent Magnetic Nanoparticle (MNP) Targeted Towards the Brain. 21st SNIP Conference, 2015 in Miami, FL, USA. J Neuroimmune Pharmacol (2015) 10(Suppl 2): S57–S112 DOI 10.1007/s11481-015-9596-y.

    ·        Sagar, Vidya., Huang, Z., Kaushik, A., Roy, U., Jayant., R.D., Atluri, V.S.R., Pilakka-Kanthikeel, S., El Hage, N., Nair, M. Effect of Magneto-electric nanoparticle on deep brain motor coordination activity. 21st SNIP Conference, 2015 in Miami, FL, USA. J Neuroimmune Pharmacol (2015) 10(Suppl 2): S57–S112 DOI 10.1007/s11481-015-9596-y.

    ·        hangavel, S., Rao, KVK., Agudelo, M., Atluri, VSR., Mulet, C., Nair, MP. HIV and Morphine: Oxidative Stress Impact Cell Cycle Regulation and Neurodegeneration. 21st SNIP Conference, 2015 in Miami, FL, USA. J Neuroimmune Pharmacol (2015) 10(Suppl 2): S57–S112 DOI 10.1007/s11481-015-9596-y.

    ·        Atluri, VSR., Pilakka Kanthikeel, S., Rao, KVK., Sagar, V., Thangavel, S., Ding, H., Roy, U., Jayant, R., Yndart, A., Raymond, A., Agudelo, M., Hernandez, O.,Fuenmayor,  M., Nair, M. Role of HDAC2 and miR-  485  in regulation of synaptic plasticity genes in HIV infection: Implication in HAND. 20th SNIP Conference, 2014 in New Orleans, Louisiana, USA. J Neuroimmune Pharmacol (2014) 9:3-64.

    ·        Sagar, V., Plakka-Kanthikeel, S., Ding, H., Atluri, V.S.R., Jayant, R.D., Kaushik, A.,   Nair, M. Novel magneto-electric nano delivery of “microRNA mimic” across the blood-brain barrier:   Implications to cocaine modulation on HIV-associated neurocognitive disorders. 20th SNIP Conference, 2014 in New Orleans, Louisiana, USA. J Neuroimmune Pharmacol (2014) 9:3-64.

    ·        Agudelo, M., Yndart,   A., Figueroa, Muñoz, K., Atluri, V.S.R.,   Thangavel, S.,   Nair, M.   Cannabinoid Agonists Regulate Alcohol-induced Inflammation in Human Dendritic Cells. 20th SNIP Conference, 2014 in New Orleans, Louisiana, USA. J Neuroimmune Pharmacol (2014) 9:3-64.

    ·        Ding, Hong.,  Yatfung,  Chiu., Raymond, Andrea., Atluri, Venkata.,  Roy, Upal.,  Yndart-Arias, Adriana., Pilakka  Kanthikeel,  Sudheesh., Sagar, Vidya., Thangavel,  Samikkannu,  Nair, Madhavan.  Development of hybrid nanocarrier (Au/Fe3O4) for active drug delivery to the brain to eliminate HIV-1 persistence. 20th SNIP Conference, 2014 in New Orleans, Louisiana, USA. J Neuroimmune Pharmacol (2014) 9:3-64.

    ·        Kurapati, KRV., Thangavel, S., Atluri, VSR.,  Yndart,  A., Nair, MPN.  Ashwagandha  (Withania somnifera)  reverses  HIV-1 induced neurodegeneration via attenuation of β-Amyloid plaques:  Implications in HIV- Associated Neurocognitive Disorders (HAND). 20th SNIP Conference, 2014 in New Orleans, Louisiana, USA. J Neuroimmune Pharmacol (2014) 9:3-64.

    ·        Pilakka Kanthikeel, S., Raymond, A., Atluri, VSR., Sagar, V., Roy, U., Yndart, A., Nair, M. SAMHD1 facilitates HIV-1 persistence:  Role of miR-155.  20th SNIP Conference, 2014 in New Orleans, Louisiana, USA.  J Neuroimmune Pharmacol (2014) 9:3-64.

    ·        Roy, Upal., Ding, H., Kanthikeel, SP., Raymond, A., Atluri, V., Yndart-Arias, A., Munoz-Caamano, K., Sagar, V., Thangavel, S., Nair, M. Magnetic nanoparticle for targetted anti-hiv drug delivery in in vivo model. 20th SNIP Conference, 2014 in New Orleans, Louisiana, USA. J Neuroimmune Pharmacol (2014) 9:3-64.

    ·        Thangavel, S., Rao, KVK., Ding, H., Agudelo, M., Atluri, VSR., Raymond, A., Perez, S., Kasturia, N., Nair, MP. Immunopathogenesis of HIV-1 Infection in Cocaine users: Role of Arachidonic Acid. 20th SNIP Conference, 2014 in New Orleans, Louisiana, USA. J Neuroimmune Pharmacol (2014) 9:3-64.

    ·        Yndart, A., Agudelo, M., Raymond, A., Atluri, VSR., Munoz-Caamano, K., Pilakka Kanthikeel, S., Sagar, V., Nair, M. Bath salts alter synaptic plasticity gene expression in neurons. 20th SNIP Conference, 2014 in New Orleans, Louisiana, USA. J Neuroimmune Pharmacol (2014) 9:3-64. J Neuroimmune Pharmacol (2013) 8:371-444.

    ·        Atluri, VSR, Sudheesh, PK, Samikkannu, T, Vijaya, P, Ding, H, Raymond, AD, Nair, M. Effect of nicotine on synaptic plasticity gene expression in HIV-1 infection: implication in HAND. 19th SNIP conference, 2013 in Puerto RicoUSA. J Neuroimmune Pharmacol (2013) 8:371-444.

    ·        Kurapati, V.K.R, Atluri, V.S.R, Samikkannu, T, Yndart, A.A, Nair, M.P.N. Ashwagandha   (Withania somnifera) reverses β-amyloid induced neuronal toxicity:  Implications in HAND.  SNIP 19th Scientific Conference, April 3-6, 2013, San Juan, Puerto Rico, USA. J Neuroimmune Pharmacol (2013) 8:371-444.

    ·        Hong Ding, Marisela   Agudelo, Sudheesh  Pilakka   Kanthikeel,   Rakesh Guduru, Vidya   Sagar, Venkata Atluri, Samikkannu Thangavel, Madhavan P. Nair. Dual Mechanism Enhanced Blood-Brain-Barrier Crossing by Transferrin conjugated Fluorescent Magnetic Liposome. SNIP 19th Scientific Conference, April 3-6, 2013, San Juan, Puerto Rico, USA. J Neuroimmune Pharmacol (2013) 8:371-444.

    ·        Pilakka-Kanthikeel, S., Raymond, A., Atluri, V., Nair, M. Cocaine downregulates SAHMD1 expression and facilitates HIV-1 infection in astrocytes. SNIP 19th Scientific Conference, April 3-6, 2013, San Juan, Puerto Rico, USA. J Neuroimmune Pharmacol (2013) 8:371-444.

    ·        Sagar, Vidya., Pilakka_kanthikeel, S.K., Priestap, H., Atluri, V.S.R., Ding, H., Guduru, R., Khizroev, S., Nair, M.P.  Magnetic-Nanoformulation of M-opioid receptor antagonist (CTOP) for treatment of morphine-induced neuropathogenesis in HIV infection.  SNIP 19th Scientific Conference, April 3-6, 2013, San Juan, Puerto Rico, USA. J Neuroimmune Pharmacol (2013) 8:371-444.

    ·        Thangavel, S, Rao, K.V.K, Raymond, A, Ding, H, Atluri, V.S.R, Nair, M.P. Immunopathogenic mechanisms of HIV-1 clade B and C:  Role of dopaminergic system. 19th SNIP conference, 2013 in Puerto Rico, USA. J Neuroimmune Pharmacol (2013) 8:371-444.

    ·        Sudheesh Pilakka-Kanthikeel, Venkata Subba Rao Atluri and Madhavan Nair. Brain-derived neurotrophic factor delivery across the blood-brain barrier using magnetic nanocarriers for neuro-protection: an in vitro study. Nanoflorida, Sept 2012, Tampa-FL.

    ·        Raymond A.D., Agudelo, M., Yndart, A., Atluri, V., Pilakka, S., Pichili, V., Hong, D., Sagar, V., Thangavel, S., Rao, K.V.K, Powell M.D., and Nair, M.  Morphine and exosomal HIV-1 Nef:  Potential roles in NeuroAIDS development. Health disparity Conference, July 11th-13th, 2012 at Univ. of North Texas, USA.

    ·        Venkata Subba Rao Atluri, Sudheesh Pilakka Kanthikeel, Madhavan P.N. Nair. Differential effects of HIV 1B and HIV-1C infection on Synaptic plasticity genes:  Implication in HIV associated neurocognitive disorders. Presented in a young investigators' poster presentation at 18th SNIP Conference, April 25-28, 2012 at Honolulu, Hawaii, USA. J Neuroimmune Pharmacol (2012) 7 (Suppl 1): S5-S81.

    ·        Goutam Mandal, Venkata Subba Rao Atluri, Anthony Franco, Martin Wiese, Barbara Papadopoulou, Hiranmoy  Bhattacharjee, Rita Mukhopadhyay.  Regulation of Leishmania aquaglyceroporin, 2010.  XXI Molecular Parasitology Meeting (MPM), 12-16 September 2010, held at Woods Hole, Massachusetts, USA.

    ·        Rita   Mukhopadhyay.,   Yao Zhou.,   Goutam Mandal., Venkata Subba Rao Atluri.,   Katherine Figarella., Nestor Uzcategui., Eric Beitz, and  Hiranmoy  Bhattacharjee.  Alanine 163 in loop C of Leishmania major aquaglyceroporin LmAQP1 resides near the pore mouth of the channel and is critical for function. 14th International Congress on Infectious Diseases held on March 9-12, 2010 in Miami, FL, USA. International Journal of      Infectious      Diseases, Volume      14, Supplement      1, March      2010, Page      e442. doi: 10.1016/j.ijid.2010.02.601.

    ·        A.V. Subba Rao, Singhi P, Khandelwal N, Malla N. Two-dimensional gel electrophoresis analysis of T. solium cysticerci  Lower  Molecular Mass (10-30  kDa)  antigens for the serodiagnosis of neurocysticercosis in children. 14th International Congress on Infectious Diseases held on March 9-12, 2010 at Miami, FL, USA. International Journal of Infectious Diseases, Volume 14, Supplement 1, March 2010, Pages e289-e290. doi: 10.1016/j.ijid.2010.02.2128.

    ·        A.V. Subba Rao, Singhi P, Khandelwal N, Malla N.  Evaluation of Lower Molecular Mass (10-30KDa) T. solium cysticerci antigen by Western blotting for the diagnosis of neurocysticercosis in children: Presented at the 13th   International   Congress on   Infectious   Diseases, Kuala   Lumpur, Malaysia- June   19-22, 2008. International Journal of Infectious Diseases, Volume 12, Supplement 1, December 2008, Pages e393-e394. doi: 10.1016/j.ijid.2008.05.1039.

    ·        A.V. Subba Rao, Singhi P, Khandelwal N, Malla N. Serodiagnosis of Neurocysticercosis in Children with the Use of T. solium cysticerci Excretory Secretory Antigens by ELISA and Immunoblotting: Presented at the 13th International Congress on   Infectious Diseases, Kuala Lumpur, Malaysia-    June   19-22, 2008. International Journal of Infectious Diseases, Volume 12, Supplement 1, December 2008, Page e394. doi: 10.1016/j.ijid.2008.05.1040.

    ·        A.V.  Subba Rao, et al., Evaluation of Crude Soluble Extract, Lower Molecular Weight (10-30KDa) and Excretory Secretory antigens of T. solium Cysticerci by ELISA for the diagnosis of neurocysticercosis in children: Presented at The Royal Society of Tropical Medicine and Hygiene One hundred years of Tropical Medicine: Meeting the millennium development goals, 13-15th September 2007, London, UK.

     

    Research Grants:

         Principal Investigator:

    ·        2022-2024: Therapeutic use of NLRP3 Inflammasome and caspase-1 inhibitors to prevent neuropathology in Alzheimer’s disease. Faculty Research Grant, NOORDA COM, Provo, Utah. Grant: $50,000

    ·        2021-20222: CRISPR/CAS9- technology to eradicate HIV-1 reservoirs in the brain and associated neurocognitive disorders. Faculty Research Grant, NOORDA COM, Provo, Utah. Grant: $25,000

    ·        2020-2021: Targeting neuroinflammation and epigenetic modifications in Alzheimer’s disease: A novel nanotechnology approach, FIU 2020 Faculty Grantsmanship Award.

    ·        2017-2021: Therapeutic Effect of Withaferin A and miR-Chimera on Alzheimer's Disease Cell Culture Models. HWCOM-FIU Pilot Grant.

         Co-Principal Investigator:

    ·        2018-2022: Therapeutic role of Withaferin A and CRID3 in the prevention of Alzheimer’s disease Associated Neuropathology. Funding Agency: Florida Department of Health. PI: Dr. M Nair.

         Co-Investigator:

    ·        NIH R01 Grant: Targeting Inflammasome with stable endocannabinoid ligand AMG315: CRISPR/Cas9 and nanotechnology study in the context of HIV and cannabinoid. National Institute of Health (NIH)- R01DA052271. PI: Dr. Madhavan Nair.

    ·        NIH R01 Grant: Multifunctional Nanocarrier to Eradicate HIV from latently infected CNS cells. National Institute of Health (NIH)-R01DA037838. PI: Dr. Madhavan Nair.

    ·       NIH R01 Grant: Nanotechnology-Based Gene Editing to Eradicate HIV Brain Reservoir in Drug Abusers. Funding Agency: National Institute of Health (NIH)- R01DA042706. PI: Dr. Madhavan Nair.

    ·       NIH R01 Grant: Nano-delivery of methanandamide across BBB to block cannabinoid-induced effects in HIV-1 infection. Funding Agency: National Institute of Health (NIH)- R01DA040537. PI: Dr. Madhavan Nair.

    ·        NIH R01 Grant: Cocaine in the Neuropathogenesis of HIV infection: Role of HDAC2. Funding Agency: National Institute of Health (NIH)- R01DA034547. PI: Dr. Madhavan Nair.

    ·        NIH R37 Grant: Role of Cocaine in Neuro-AIDS by HIV 1B and C Clades. Funding Agency: National Institute of Health (NIH)- R37DA025576. PI: Dr. Madhavan Nair.

    ·        NIH R21 Grant: Novel Magneto-Electric Nanodelivery of Drugs to Eradicate HIV from CNS.  Funding Agency:  National Institute of Health (NIH)- R21MH101025. PI: Dr. Madhavan Nair.

    ·        NIH R01 Grant: Polydrug Nanocarrier to Treat Opiate Addiction and HIV Disease. Funding Agency: National Institute of Health (NIH)- R01DA027049. PI: Dr. Madhavan Nair.

    ·        NIH R01 Grant: Mechanisms of Neuro-AIDS by HIV1B and C Clades. Funding Agency: National Institute of Health (NIH)- R01MH085259. PI: Dr. Madhavan Nair.

     


  • Berkowitz, Murray

    Research Interest:

    • Neuromusculoskeletal Medicine and Osteopathic Manipulative Medicine
    • Preventive Medicine and Public Health
    • Consortium for Collaborative Osteopathic Research Development - Practice Based Research Network

    Scholarly Work:

    • Berkowitz MR; “Osteopathic Approach to Treating a Patient with Congenital Infantile Torticollis reveals Unusual Presentation of Absence of Concomitant Cranial Base Strain Pattern:  A Case Report”; International Journal of Osteopathic Medicine (2017) 25:46-48.available online at http://dx.doi.org/10.1016/j.ijosm.2017.03.002
    • Berkowitz, MR; “Obliterated Temporomandibular Joint”; Journal of the American Osteopathic Association (2017) 117(8):542  Available online at http://dx.doi.org/10.7556/jaoa.2017.107
    • *Ignatowicz A and Berkowitz MR; “Imaging Evidence Demonstrating Effectiveness of Osteopathic Visceral Manipulation Techniques in Treating Pseudo-Obstruction”; American Academy of Osteopathy Journal (2017) 27(1):7-10.
    • *Wernick HJ, Berkowitz MR; “Osteopathic Manipulative Treatment for Infants in the NICU: A Systematic Review”; Acta Scientific Medical Sciences (2019) 3(10):35-44.
    • *Philipps SM, Berkowitz MR (2019)  "Analyzing Predictive Factors Associated with the Variable Rates of Prevalence of Post-Traumatic Stress Disorder among National Guard/Reserve Soldiers Compared to Active Duty Soldiers:  A Pilot Study."  Psychology, 10, 2224-2246. Available online at https://doi.org/10.4236/psych.2019.1016141
    • Berkowitz MR; “Examination of ‘The Tide’, CRI, and Physiologic Respiration”; American Academy of Osteopathy Journal (2023) 33(2):54-60.
    • Berkowitz MR; “The Use of Osteopathic Manipulative Treatment for Treatment of Sore Throat, Headache and Facial Pain:  A Case Report”; American Academy of Osteopathy Journal (2023) 33(3):21-24.
    • Berkowitz MR; “Osteopathic Manipulative Treatment for Treatment to Treat Patients with Long-Haul COVID Loss of Smell and Taste:  A Report of Four Cases”; American Academy of Osteopathy Journal (2023) 33(4):16-19.
    • Berkowitz, MR; “Osteopathic Approach to a Patient with Recurring Low Back Pain following OMT results in Diagnosis of Underlying Gynecologic Etiology:  A Case Report”; American Academy of Osteopathy Journal (2024) 34(1):25-30.

  • Dr. George Msom

    Research Interest:

    • Research interests include population and community health and primary care innovation
    • Author and speaker on physician leadership development, models of care delivery, and quality improvement

    Scholarly Work:

    ·        Kadavakollu S, George AE, Gregory P. How to Prepare for the Comprehensive Osteopathic Medical Licensing Examination of the USA Level 2-Cognititive Evaluation (COMLEX-USA Level 2-CE). The International Journal of Osteopathic Medicine. Under Editorial Review with Revisions Requested.

    ·        Hoffmann K, Wojczewski S, Rumpler N, George AE, Boeckxtaens P. Giving Patients a Voice for Healthcare Reform in Austria: The Qualitative Voice-Study. Family Practice. 2024;41(5):790-797. doi: 10.1093/fampra/cmae031. PMID: 38795059; PMCID: PMC11461150.

    ·        Joshi M, George AE. Healthcare Transformation. A Guide for the Hospital Board Member. CRC Press, October 2024. (Textbook)

    ·        Bonatti H, Frushour C, George AE. Vitamin C and Thiamin Deficiencies in Patients Undergoing Laparoscopic and Robotic Gastric Band Removal. The American Surgeon. 2024;90(8):2132-2134. doi: 10.1177/00031348241244630. PMID: 38567434.

    ·        Karunarante J, Gona S, George AE, Bonatti H. Acute Cholecystitis Due to Lactococcus lactis and Single-Center Experience with Infections Due to Lactocossus spp. Surgical Infections. 2024;25(4):332-334. doi: 10.1089/sur.2024.042. PMID: 38696668.

    ·        Joshi M, George AE. Leading Health Care Transformation: A Primer for Physician Leaders. CRC Press October 2023. (Textbook)

    ·        Bonatti, H, Gona SR, Feaga C, George AE. Hypothyroidism Complicated by Vitamin C and Thiamin Deficiency in Surgical Patients. The American Surgeon. 2023;89(9):3835-3837. doi: 10.1177/00031348231175098. PMID: 37278003.

    ·        Jawaid M, El-Sherif T, George AE, Bonatti H. Acute Cholecystitis in a Gastric Bypass Patient Complicated by Takotsubo Cardiomyopathy. Case Reports in Surgery. 2022, Article ID 5416092.  doi: 10.1155/2022/5416092. PMID: 35845615; PMCID: PMC9278497.

    ·        Bonnet JP, George AE. The Doctor Will See You After Your Workout. American Journal of Lifestyle Medicine. 2021 Jan 20;15(3):238-241. doi: 10.1177/1559827620988284. PMID: 34025313; PMCID: PMC8120611.

    ·        George D, George AE, George KL. Big Data Just Got Bigger: Implications of Real-World Evidence and Patient-Entered Data on Healthcare and Healthcare Policy. American Journal of Lifestyle Medicine. 2019;14(1):40-42. doi: 10.1177/1559827619882605. PMID: 31903079; PMCID: PMC6933559.

    ·        Hoffman K, Ristl R, George AE, Maier M, Pichlhofer O. The Ecology of Medical Care: Access Points to the Health Care System in Austria and Other Developed Countries. Scandinavian Journal of Primary Health Care. 2019;37(4):409-417.  doi: 10.1080/02813432.2019.1663593. PMID: 31512566; PMCID: PMC6883430.

    ·        Hoffman K, George AE, Van Leonen T, De Maeseneer J, Maier M. The Influence of General Practitioners on Access Points to Health Care in a System Without Gatekeeping: a Cross-Sectional Study in the Context of the QUALICOPC Project in Austria. Croatian Medical Journal. 2019;31(4):316-324. doi: 10.3325/cmj.2019.60.316. PMID: 31483117; PMCID: PMC6734571.

    ·        Hoffman K, George AE, Jirovsky E, Dorner TE. Re-Examining Access Points to the Different Levels of Health Care: a Cross-Sectional Series in Austria. European Journal of Public Health. 2019;29(6):1005-1010. doi: 10.1093/eurpub/ckz050. PMID: 30938408; PMCID: PMC6896971.

    ·        Gaudiose M, George AE. Comments on ‘Work-Life Balance, Burnout, and the Electronic Health Record’. American Journal of Medicine. 2019;132(4)e:546. doi: 10.1016/j.amjmed.2018.11.033. PMID: 30935462.

    ·        George AE, Sachdev N, Hoff J, Bord S, Weida T, O’Connor M, Davis KN. Development, Value, and Implications of a Comprehensive Primary Care Payment Calculator for Family Medicine Report From Family Medicine for America’s Health Payment Tactic Team. Family Medicine. 2019;51(2):185-192. doi: 10.22454/FamMed.2019.286478. PMID: 30736045.

    ·        Phelan D, George AE, Meyer T. Current Trends in Medical Education, What Does Our Future Hold? Maryland Medicine. 2016;17(1):23-4. PMID: 27443126.

    ·        Shaw RJ, Steinberg D , Bonnet J, Modarai  F, George AE, Cunningham T, Mason  M, Shahsahebi  M, Grambow SC, Bennett G, Bosworth H. Mobile Health Devices: Will Patients Actually Use Them? Journal of the American Medical Informatics Association. 2016;0:1-5  doi:10.1093/jamia/ocv186

    ·        Hoffmann K, George AE, Dorner TE, Sub K, Schafer WL, Maier M. Primary Health Care Teams Put to the Test. BMC Family Practice. 2015;16(1):168 doi: 10.1186/s12875-015-0384-9. doi: 10.1186/s12875-015-0384-9. PMID: 26572224; PMCID: PMC4647311.

    ·        Hoffmann K, van Bijnen EM, George AE, Kutalek R, Jirovsky E, Wojczewski S, Maier M. Associations Between the Prevalence of Influenza Vaccination and Patient’s Knowledge about Antibiotics: A Cross-Sectional Study in the Framework of the APRES-project in Austria. BMC Public Health. 2015;15(1):981. doi: 10.1186/s12889-015-2297-x. PMID: 26416304; PMCID: PMC4587920.

    ·        Hoffmann K, Wojczewski S, George AE, Schafer W, Maier M. Stressed and Overworked? A Cross-Sectional Study of the Working Situation of Urban and Rural General Practitioners in Austria in the Framework of the QUALICOPC Project. Croatian Medical Journal. 2015;56(4):366-74. doi: 10.3325/cmj.2015.56.366. PMID: 26321030; PMCID: PMC4576751.

    ·        Hoffmann K, Peersman W, George AE, Domer TE. Associations and Synergistic Effects for Psychological Distress and Chronic Back Pain on the Utilization of Different Levels of Ambulatory Health Care. PLoS One. 2015;10(7). doi: 10.1371/journal.pone.0134136. PMID: 26218661; PMCID: PMC4517760.

    ·        George AE. A Potential Unexpected Consequence of Drug Shortages on Long-Term Prescribing Patterns.  American Journal of Health-System Pharmacy. 2015;72(11):916. doi: 10.2146/ajhp140199. PMID: 25987683.

    ·        George AE. Hold on One Second: Interrupting the Intern Year. Medical Education. 2015;49(5):451-3. doi: 10.1111/medu.12746. PMID: 25924118.

    ·        Hoffmann K, den Heijer CD, George AE, Apfalter P, Maier M. Prevalence and Resistance Patterns of Commensal S. Aureus in Community-Dwelling GP Patients and Socio-Demographic Associations. BMC Infectious Diseases. 2015;15:213. doi: 10.1186/s12879-015-0949-1. PMID: 25981559; PMCID: PMC4458027.

    ·        Hoffman K, George AE, Heschel L, Leifheit AK, Maier M. Oral Contraceptives and Antibiotics. A Cross-Sectional Study about Patients’ Knowledge in General Practice. Reproductive Health. 2015;12:43. doi: 10.1186/s12978-015-0037-4. PMID: 25971980; PMCID: PMC4438508.

    ·        Shaw RJ, Bonnet JP, Modarai F, George AE, Shahsehebi M. Mobile Health Technology for Personalized Primary Care Medicine. American Journal of Medicine. 2015;128(6):555-557.  doi: 10.1016/j.amjmed.2015.01.005. PMID: 25613298.

    ·        Bonnet JP, George AE, Evans P, Silberberg M, Dolinsky D. Rethinking Obesity Counseling: Having the French Fry Discussion. The Journal of Obesity. Vol. 2014, Article ID 525021. doi: 10.1155/2014/525021. Epub 2014 Oct 19. PMID: 25386360; PMCID: PMC4217316.

    ·        George AE, Frush KS, Michener JL. Developing Physicians as Catalysts for Change. Academic Medicine. 2013;88(11). doi: 10.1097/ACM.0b013e3182a7f785. PMID: 24072124.

    ·        George AE, Joshi M. The Value of Less: Improving Patient Care by Reducing Unnecessary Procedures. NEJM Catalyst. October 19, 2022. Published at: https://catalyst.nejm.org/doi/full/10.1056/CAT.22.0200

    Selected Presentations:

    ·        June 2024   "Osteopathic Manipulative Treatment in the Seated Patient,” Pennsylvania Academy of Family Physicians Annual CME, Dewey, DE

    ·        April 2024   "Pathways in Primary Care,” Duke Family Medicine Residency, Durham, NC

    ·        October 2023 "Beyond Pipelines: Inspiring Pathways to Family Medicine,” Family Medicine Education Consortium, Alexandria, VA

    ·        July 2023 “Osteopathic Medicine,” Primary Care Scholars Program, Penn State College of Medicine

    ·        June 2024 “Osteopathic Manipulative Medicine Workshop,” Pennsylvania Academy of Family Physicians Annual CME, Dewey, DE

    ·        June 2024 “Office Based Dermatologic Procedures Workshop,” Pennsylvania Academy of Family Physicians Annual CME, Dewey, DE

    ·        April 2023 “Reducing Low-Value Care,” Presentation to the National Low-Value Care Collaborative

    ·        September 2022 “The Changing Landscape of Recruitment – Recruiting a More Diverse Intern Class,” Family Medicine Education Consortium, Pittsburgh, PA

    ·        July 2022 “Humanizing the Healthcare System and Dissecting the Complex: Family Physicians as Leaders” AAFP National Conference, Kansas City, MO

    Book Chapters Authored:

    ·        George AE, Lutzkanin A,‘Value-Based Care’ In Rakel’sTexbook of Family Medicine. 10th Edition. Accepted

    ·        George AE, ‘Effective Media Relations’ In The Chief Medical Officer’s Essential Guidebook. AAPL Press 2023 

    ·        Zanetti C, George AE, Stiegmann R, Phelan D. ‘Digital Health’ In The Efficacy of Training Programs and Systems in Medical Education IGI Global, 404-426, 2020

    ·        DesRosiers, TD, George AE, Stack S. (2019) ‘Federal Advocacy’, in Strauss RW, Mayer TA. (2nd ed.) Strauss and Mayer’s Emergency Department Management. ACEP, 2071-2088, 2021


  • Samuel Kadavakollu 2

    Research Interest:

    • Integration of nutrition, community health, preventive medicine, research methodology, diversity, equity, & inclusion topics into osteopathic medical school curriculum
    • Curriculum design, delivery, assessment, and continuous quality improvement for osteopathic medical education
    • Promoting Cultural Competence and Osteopathic Medicine Awareness Among Premedical Students
    • Helping osteopathic medical students with their Comprehensive Osteopathic Medical Licensing Examinations

    Scholarly Work:

    • "Fostering a Research Culture in Osteopathic Medical Education." Journal Osteopathic Medicine, 2024, 1, 1-2 
    • "A Comprehensive Review of Clinical Experiences and Extracurricular Activities for US Premedical Students Applying to Osteopathic Medical Schools." Journal Osteopathic Medicine, 2024, 1, 1-10
    • “5-C’s Tips Approach to Preparation for the Comprehensive Osteopathic Medical Licensing Examination USA Level 2- Cognitive Evaluation (COMLEX USA Level 2-CE).” International Journal of Osteopathic Medicine, 2024, Manuscript in Preparation.
    • "Six Practical Tips to Prepare for the Comprehensive Osteopathic Medical Licensing Examination (COMLEX) USA Level 1." International Journal of Osteopathic Medicine, 2023, 49, 1-9.
    • "Pre-professional Student Perceptions of Team-Based Learning Applied in a Medical College Admission Test Preparatory Course." SN Social Sciences, 2023, 1, 1-10.
    • "Promoting Cultural Competence and Osteopathic Medicine Awareness Among Premedical Students Through a Summer Premedical Rural Enrichment Program (PREP)." Journal Osteopathic Medicine, 2022, 1, 1-9.
    • "Pre-med Pathway Bootcamps – Guiding Students of the California Central Valley Towards Medicine" Presentation on Recruitment, The AACOM Annual Conference, Educating Leaders, April 29th, 2022. 

  • Nicewarner Martin   Edit

    Research Interest:

    • Learning disabilities
    • Forensic pathology
    • Creating physicians that I would trust to take care of my family members

    Scholarly Work:

    • Distance from the Uterine Body to the Uterine Artery-Ureter Crossover Point in Female Cadavers, Kalu George U, Theobalt K, Turk M, Martin MJ
    • KCU Research Symposium, March 2023, Poster presentation: Joplin, MO
    • The diagnosis of malaria in nonendemic areas: Giemsa-stained thick and thin blood smear versus rapid diagnostic tests (RDTs)- A Case Report, Igwacho Erin, Adefuye Anthonio, Martin MJ, KCU Research Symposium, March 2023, Poster presentation: Joplin, MO
    • The diagnosis of malaria in nonendemic areas: Giemsa-stained thick and thin blood smear versus rapid diagnostic tests (RDTs)- A Case Report, Igwacho Erin, Adefuye Anthonio, Martin MJ, Student National Medical Association at the Annual Medical Education Conference, 2023, Poster presentation: Wilbert C. Jordan Student Research Forum (WCJRF), Hartford CT

    Presentations/talks/other contributions:

    • KCU Homecoming speaker, KC (Sept 2023) Forensic Cases & Death Certificates “Detoured: an ADHD Exploration” podcast, July 13, 2023, guest Drury University Pre-Health Club speaker (3-8-2023) Pathology & Forensics
    • KCU Magazine, Fall 2022 The Science of Solved; A Breathless Pursuit, Subject of article Alexander-Passe N. Invisible Differences, Visible Success. Dio Press Inc, New York 2022
    • Chapter subject/collaborator book about individuals with invisible “disabilities”.

  • Raena Pettitt 1

    Research Interest:

    • Role of Osteopathic family physician, medical education

    Scholarly Work:

    ·        Hoegerl C, Barton A, Pettitt R (January 22, 2023) Innovation in Learning: Critical Review of the Literature Is Absolutely Necessary for the Modern Medical Student. Cureus 15(1): e34055.doi:10.7759/cureus.34055

    ·        Pettitt R.M., Brown E A, Delashmitt J C, et al. (October 12, 2022) The Management of Anxiety and Depression in Pediatrics. Cureus 14(10): e30231. doi:10.7759/cureus.30231

    ·        Pettitt, R.M., Horkott, G.B., Reno, D.C., Grohol, B.N. (2022) An Osteopathic Approach to Anemia, Osteopathic Family Physician, 14 (5), 10-15

    ·        Pettitt, R.M, Gara, T.M, Izak, M.E., Steele, E.R (2022) The Impact of Climate Change on our Patients’ Health and the Family Physician’s Role, Osteopathic Family Physician, 14 (4), 35-40

    ·        Speaker at the Virginia Osteopathic Medical Association Fall Conference, entitled “Sexually Transmitted Infections”, October 2021

    ·        Poster Presentation for the American Academy of Osteopathic Family Physicians-Breast Abscess: A Rare Complication of a Common Complaint, co-authored with J. Stuart May, MD, and Janelle Hartman, OMS-III, February 2021

    ·        Pettitt, R.M., Brumbaugh, A.P, Gartman, M.F., Jackson, A.M., (2020) Chronic Kidney Disease: Detection and Evaluation, Osteopathic Family Physician,12(1), 14-19

    ·        Hadfield, M.J, Kota, S.V., Siragusa, S.M., Pettitt, R.M. (2019). Skin & Soft Tissue Infections: It’s More Than Just MRSA. Osteopathic Family Physician, 11(1), 28-32

    ·        Pettitt, R.M., Ilustrisimo, T.L., Song, J.Y., Kim, A.J. (2018). Newborn Disorders and Nutritional Guidance, Osteopathic Family Physician 10(6), 20-26

    ·        Pettitt, R.M., Kota, S.V., Hadfield, M.J., (2017) Abnormal Loss of Weight. Osteopathic Family Physician, 9(2), 20-24


  • Chante Richardson

    Research Interest:

    • Using service-learning approaches in community health
    • Health disparities (Breast, Prostate, and Lung Cancer)

    Scholarly Work:

    ·        “Teaching Biochemistry to Students of Dentistry, Medicine, and Pharmacy 9th International Conference of the Association of Biochemistry Educators (ABE) Kiawah

    ·        Island, South Carolina, April 30–May 4, 2023.” Medical Science Educator, (2023).

    ·        “Inflammatory Biochemical Mediators and Their Role in Myofascial Pain and Osteopathic Manipulative Treatment: A Literature Review.” Cureus Journal of Medical Science, 14(2). (2022).

    ·        Reviewer for “Lippincott's Illustrated Reviews: Biochemistry, 8th Edition.” Wolters Kluwer. (2021)

    ·        "A Grassroots Approach to Reduce Social and Health Disparity through Medical School Service Education," Educating Leaders 2022, AACOM Annual Conference, (2022).

    ·        "I Have a Dream -Striving to Meet the Long-overdue Need for Diversity and Inclusion in Medical Education," Educating Leaders 2021, AACOM Annual Conference, (2021).


  • Singh

    Research Interest:

    • New NQO1 bioactivatable drug class
      • Deoxynyboquinone (DNQ) derivatives.
      • Synergize with PARP inhibitors
    • Radiosensitizing effect of New NQO1 bioactivatable drug
      •  IR sensitization, synergize well with IB-DNQ
    • NQO1 bioactivatable drug effect on the immune system
      • Innate or adaptive immunity, synergize with PD-1/PD-L1

    Scholarly Work:

    ·        Naveen Singh, Joshua E. Lewis, Reetta J. Holmila, Baran D. Sumer, Noelle S. Williams, Cristina M. Furdui, Melissa L. Kemp, David A. Boothman. Targeting NAD+ metabolism to enhance radiation therapy responses. Seminars in Radiation Oncology, Elsevier: 2019; pp 6-15.

    ·        Edward A. Motea, X. H., Naveen Singh, Jessica A Kilgore, Noelle S. Williams, Xian-Jin Xie,

    ·        David E. Gerber, Muhammad Beg, Erik A. Bey; Boothman, D. A., NQO1-dependent, tumorselective radiosensitization of non-small cell lung cancers. Clinical Cancer Research 2019.

    ·        Kahanda D, Singh N, Boothman DA, Slinker JD. Following anticancer drug activity in cell

    lysates with DNA devices. Biosens Bioelectron. 2018 Jul 30;119:1-9.

    ·        Chen X, Mims J, Huang X, Singh N, Motea EA, Planchon SM, Beg M, Tsang AW, Porosnicu M, Kemp ML, Boothman DA, Furdui C. Modulators of Redox Metabolism in Head and Neck Cancer. Antioxid Redox Signal. 2017

    ·        Lyday RW, Etters MA, Kim C, Magana F, Pontipiedra GM, Singh N and Kadavakollu S*,

    PDE5 Inhibitors Offer Novel Mechanisms in Combination and Solo Cancer Therapy, Current Cancer Therapy Reviews, 2017.


  • Vasauskas

    Research Interest:

    • Endothelial biology, health and dysfunction
    • Proactive wellness; nutrition, exercise, OMT on vagal tone, blood flow, stress biomarkers
    • Medical education

    Scholarly work:

    ·        Miller A, Gustin D, Wilson J, Johns J, Fotopoulos TJ, Garg R, and Vasauskas AA, Autonomic Rehabilitation: Vagal and Sympathetic Impacts of Modified Occipitomastoid Suture V-Spread. PM&R: The Journal of Injury, Function and Rehabilitation. doi: 10.1002/pmrj.13268. 2024

    ·        Chosie K, Helms J, and Vasauskas A, Twelve tips for developing institutional student-faculty-staff boundaries guidelines and training. MedEd Publish. doi:10.12688/mep.20605.1. 2024

    ·        Ganesan PR and Vasauskas AA. The Association Between Pica and Iron-Deficiency Anemia: A Scoping Review. Cureus Journal of Medical Science. doi: 10.7759/cureus. 2023

    ·        Sinopoli HJ, Vasauskas AA. Examination of Ankle Trauma in United States Military Members: A Scoping Review. Cureus Journal of Medical Science. 14(12): e32175. doi: 10.7759/cureus.32175. 2022.

    ·        Kwon MJ, Hamilton CL, Brown JR, Snyder EA, and Vasauskas AA. FK506 Binding protein 51 colocalizes with microtubules and may contribute to metabolic abnormalities by directing glucocorticoid receptor localization in pulmonary artery endothelial cells isolated from the Sugen rat model of pulmonary arterial hypertension. Journal of the American College of Cardiology. 79 (9 supplement, 1663).  2022.

    ·        Ibiwoye, MO, Snyder EA, Lyons J, Vasauskas AA, Hernandez MJ, Summerlin AR, and Foster JA. The Effect of Short-Term Exposure to Cadmium on the Expression of Vascular Endothelial Barrier Antigen in the Developing Rat Forebrain and Cerebellum: A Computerized Quantitative Immunofluorescent Study. Cureus. 14(4): e23848. doi:10.7759/cureus.23848. 2022

    ·        Buttars B, Olsen J, McClean J, Fountain L, Goodwin J, Grant W, Hatton T, Clemmons M, Vasauskas A, Hamilton C. The Impact of Community-Generated PPE during the SARS-COV2 Pandemic. Frontiers in Health Services. 2021. doi: 10.3389/frhs.2021.786062

    ·        Decker EP and Vasauskas AA. Lung Epithelial Protein Expression and the Use of Volatile Anesthetics in Acute Respiratory Distress Syndrome. The Cureus Journal of Medical Science. Cureus 12(9): e10196. doi:10.7759/cureus.10196, 2020.

    ·        Hamilton CL, Kadeba PI, Vasauskas AA, Solodushko V, McClinton AK, Alexeyev M, Scammell JG, Cioffi DL. Protective role of FKBP51 in calcium entry-induced endothelial barrier disruption. Pulmonary Circulation. 8(1):2045893217749987, 2018.

    ·        Hamilton CL, Abney KA, Vasauskas AA, Alexeyev M, Li N, Honkanen RE, Scammell JG, Cioffi DL. Serine/Threonine phosphatase 5 (PP5C/PPP5C) regulates the ISOC channel through a PP5C-FKBP51 axis.  Pulmonary Circulation. 8(1):2045893217753156, 2018.

    ·        Hernandez MJ, Giannini J, Alston S, Vasauskas AA. Use of live-stream and pre-recorded simulation in the individual readiness assessment test during TBL, a Novel Approach. Medical Science Educator. 27: 15-19, 2016.

    ·        Vasauskas AA. The integration of oneself into a medical school curriculum. Medical Science Educator. 4: 545-547, 2015.

    ·        Vasauskas AA, Chen H, Wu S, Cioffi DL.  The serine-threonine calcium/calmodulin-activated phosphatase calcineurin is involved in regulation of store-operated calcium entry.  Pulmonary Circulation. 4:16-27, 2014.

    ·        Parra-Bonilla, G, Alvarez D, Alexeyev A, Vasauskas A, and Stevens, T.  Lactate Dehydrogenase A Expression is Necessary to Sustain Rapid Angiogenesis of Pulmonary Microvascular Endothelium. PLoS one. 8:e75984, 2013.

    ·        Kadeba PI, Vasauskas AA, Chen H, Wu S, Scammell JG, Cioffi DL.  2013.  Regulation of store-operated calcium entry by FK506-binding immunophilins.  Cell Calcium. 53: 275-85, 2013.

    ·        Vasauskas A, Schuler AM, Olatinwo M, Scammell JG.  Expression of pituitary chorionic gonadotropin in New World primates.  In “Clinical Infertility and In Vitro Fertilization.”ed. Rizk, B., Sallam H.N.  Jaypee Brothers Medical Publishers Pvt. Ltd. 2012. (BOOK CHAPTER)

    ·        Vasauskas AA, Hubler TR, Boston L, Scammell JG. Tissue-specific expression of squirrel monkey chorionic gonadotropin.  General and Comparative Endocrinology.  170:514-21, 2010.

    ·        Vasauskas AA, Hubler TR, Mahanic C, Gibson S, Kahn AG, Scammell JG.  Squirrel monkey pituitary chorionic gonadotropin is coregulated and costored with secretogranin II. General and Comparative Endocrinology 170: 509-13, 2010.

    ·        Ghanbari H, Ghanbari K, Beheshti I, Munzar M, Vasauskas A, and Averback P. Biochemical Assay for AD7C-NTP in Urine as an Alzheimer’s Disease Marker. Journal of Clinical Laboratory Analysis, Vol. 12:285-288, 1998.

    Meeting proceedings

    ·        Vasauskas A and Choby B. Research Alive! Creating an innovative research curriculum that fosters students. Generalists in Medical Education Annual Meeting. 2024. (accepted)

    ·        Miller A, Gustin D, Wilson J, Johns J, Fotopoulos TJ, Garg R, and Vasauskas AA,

    Occipitomastoid Suture V-spread Increases Vagal Tone and Decreases Sympathetic Activity as Quantified by Heart Rate Variability Metrics. American Academy of Physiatry Annual Meeting. 2023.

    ·        Brown JR, Conner A, Snyder EA, Vasauskas AA. Forkhead Box O3 (FOXO3) Protein Levels are Elevated in a Model of Pulmonary Arterial Hypertension. Society of Hospital Medicine, Wiregrass Chapter Annual Meeting. Dothan, Alabama. December 2022. (SECOND PLACE, Basic Science Research category)

    ·        Telese RQ, Ibiwoye MO, Vasauskas AA, Hernandez MJ, Lyons J, Foster JD. The Vascular Endothelial Barrier Antigen is Differentially Expressed in the Developing Forebrain and Cerebellum of Healthy Rats as Quantitated by Immunofluorescent Microscopy. Society of Hospital Medicine, Wiregrass Chapter Annual Meeting. Dothan, Alabama. December 2022. (THIRD PLACE, Basic Science Research category)

    ·        Wu E, Weiss J, Barefield AB, Alexander VS, Kassis N, Akbar MD, Vasauskas, AA.

    Preliminary Results of Proactive Patient Portal Recruitment in the Inpatient Setting: The MyChart Genius Project. Society of Hospital Medicine, Wiregrass Chapter Annual Meeting. Dothan, Alabama. December 2022 (THIRD PLACE, Clinical Research and QI category)

    ·        Kwon, M, Hamilton CL, Brown JR, Snyder EA, and Vasauskas AA. FK506 binding protein 51 colocalizes with microtubules and may contribute to metabolic abnormalities by directing glucocorticoid receptor localization in pulmonary artery endothelial cells isolated from the Sugen rat model of pulmonary arterial hypertension. American College of Cardiology. Washington DC April 2022.

    ·        Vasauskas AA, Mitchell N, and Ennis L. Creating A Research Culture at An Osteopathic Medical School. American Academy of Colleges of Osteopathic Medicine. Denver CO April 2022.

    ·        Richardson C, Mitchell N, Vasauskas AA, and Ennis L.  A Grassroots Approach to Reduce Social And Health Disparity Through Medical School Service Education. American Academy of Colleges of Osteopathic Medicine. Denver CO April 2022.

    ·        Snyder EA and Vasauskas AA. 5-hydroxytryptamine receptor expression is downregulated in pulmonary artery endothelial cells isolated from a rat model of PAH. Society of Hospital Medicine, Wiregrass Chapter Annual Meeting. Dothan, Alabama November 2021.

    ·        Tomes J, Vasauskas AA, Hamilton C, Brown JR. BMP4 and LPS stimulation leads to elevated Akt signaling in PAH endothelial cells.  Society of Hospital Medicine, Wiregrass Chapter Annual Meeting. Dothan, Alabama November 2021.

    ·        Jay JH, Vergara F, Vasauskas AA, Hanserd M. #TopDocs: The Top 50 Instagram Physician Influencers. Society of Hospital Medicine, Wiregrass Chapter Annual Meeting. Dothan, Alabama November 2021

    ·        Hamilton CL, Thompson SM, Snyder EA, Brown JR, and Vasauskas AA. Membranous Expression of Integrin α5β1 is Elevated in Endothelial Cells of Pulmonary Arterial Hypertension. Experimental Biology. Virtual. April 2021.

    ·        Vasauskas, AA, Segui E, and Ennis L. Thinking outside the [research] box: alternative summer research experiences for medical students. American Academy of Osteopathic Medicine. Virtual. April 2021.

    ·        Snyder E, Brown JR, and Vasauskas AA., ID-1 expression as an indicator of BMPR2 signaling abnormalities in isolated pulmonary artery endothelial cells from a rat model of PAH. Society of Hospital Medicine Wiregrass Chapter Annual Meeting. Dothan, AL. November 2020.

    ·        Bettridge A, Morley T, Iyer G, Vasauskas AA, and Morrow KA. Osteopontin levels are decreased in pulmonary artery endothelial cells that show evidence of endothelial to mesenchymal transition. Society of Hospital Medicine Wiregrass Chapter Annual Meeting, Dothan, AL. November 2020.

    ·        Martin H, Vasauskas AA, Hamilton C, Brown JR. BMP4 stimulation leads to elevated Akt signaling in PAH endothelial cells. Society of Hospital Medicine Wiregrass Chapter Annual Meeting. Dothan, AL. November 2020.

    ·        Davidson VR, Brown JR, Vasauskas AA, Hamilton C. Increased microtubule density in PAH endothelial cells. Society of Hospital Medicine Wiregrass Chapter Annual Meeting. Dothan, AL. November 2020.

    ·        Morley TJ, Bettridge A, Morrow RM, Vasauskas AA. Legumain – A new player in PAH pathogenesis? Society of Hospital Medicine Wiregrass Chapter Annual Meeting. Dothan, AL. November 2020

    ·        Carbungco JK, Green H, Lowdon V, Chosie K, Hamilton C, and Vasauskas, AA. Stressed Out Medical Students and How to Define Them; Tracking Anxiety, Stress, and Coping during Years I and II. American Academy of Osteopathy, Colorado Springs, CO. March 2020.  (FIRST PLACE, Research Poster Presentation).

    ·        Hamilton C, Snyder E, West B, and Vasauskas AA. Microtubule Arrangement and FKBP51 Localization is Altered in BMPR2-Deficient Pulmonary Artery Endothelial Cells Isolated from a Rat Model of PAH. Experimental Biology. April 2020 (accepted, meeting canceled)

    ·        West B, Brown JR, Morrow R, Morrow KA, Hamilton C, and Vasauskas AA. Nuclear localization of FKBP51 may alter inflammatory signaling in pulmonary arterial hypertension through the NFκB pathway. Medical Student Association of the State of Alabama (MASA). April 2020. (accepted, meeting canceled).

    ·        Guice KC, Hamilton C, Morrow RL, Morrow JA, Brown JB, and Vasauskas AA. Pulmonary artery endothelial cells exhibit reduced glucocorticoid responsiveness in pulmonary arterial hypertension. Society of Hospital Medicine, Wiregrass Chapter Annual Meeting. Dothan, Alabama October 2019.

    ·        Johnson J, Vasauskas AA, Hamilton CL, Morrow RL, Morrow KA, and Brown JR. Pulmonary Endothelial Cells from the Sugen5416/hypoxia PAH model exhibit hyperproliferation and elevated Akt activation. Society of Hospital Medicine, Wiregrass Chapter Annual Meeting. Dothan, Alabama October 2019.

    ·        Pace-Patterson AM, Brown, JR, Hamilton CL, Morrow KA, Vasauskas AA, and Morrow RL.The Effects of TGFβ on EndMT in PAH cells. Society of Hospital Medicine, Wiregrass Chapter Annual Meeting. Dothan, Alabama October 2019.

    ·        Miley MC, Hamilton CL, Morrow RL, Brown JR, Vasauskas AA, and Morrow KA. Pseudomonas aeruginosa Infection Reveals Endothelial Heterogeneity of Cells Predisposed to Pulmonary Arterial Hypertension. Society of Hospital Medicine, Wiregrass Chapter Annual Meeting. Dothan, Alabama October 2019.

    ·        Koch SA, Brown JR, Morrow KA, Morrow RL, Vasauskas AA, and Hamilton CL. Dexamethasone impairs wound resealing in pulmonary artery endothelial cells. Society of Hospital Medicine, Wiregrass Chapter Annual Meeting. Dothan, Alabama October 2019.

    ·        Shoham S, Morrow RL, and Vasauskas AA.  The search for cellular models of pulmonary arterial hypertension. Medical Association of the State of Alabama (MASA). Birmingham, AL, April 2019.

    ·        Sue GJC, Morrow RL, Robinson AL, Segui E, and Vasauskas AA. Medical student wellness - Do yoga and meditation help? Medical Association of the State of Alabama (MASA). April 2019.

    ·        Morrow KA, Brown JR, Morrow RL, Snyder EA, and Vasauskas AA. Evidence of endothelial-to-mesenchymal transition in an animal model of pulmonary arterial hypertension. Experimental Biology. April 2019.

    ·        Gonzalez M, Morrow RL, Brown JR, Morrow KA, and Vasauskas AA. Endothelial to mesenchymal transition in pulmonary arterial hypertension. 96th Annual Meeting of the Alabama Academy of Sciences. Tuskegee AL, February 2019. (FIRST PLACE Oral presentation – M. Gonzalez)

    ·        Gonzalez M, Carter AG, Cullifer JT, Vasauskas AA, Morrow RL, Brown J, Morrow KA. Altered Intracellular Osteopontin and Merlin Signaling May Drive Endothelial-to-Mesenchymal Transition in BMPR2 Deficient Pulmonary Artery Endothelial Cells. Society of Hospital Medicine, Wiregrass Chapter Annual Meeting. Dothan, Alabama September 2018.

    ·        Carter AG, Cullifer JT, Gonzalez M, Vasauskas AA, Morrow RL, Brown J, Morrow KA. Pulmonary Endothelial Cells Predisposed to PAH Have Increased Sensitivity to Pseudomonas aeruginosa Infection. Society of Hospital Medicine, Wiregrass Chapter Annual Meeting. Dothan, Alabama September 2018.

    ·        Cullifer JT, Carter AG, Gonzalez M, Vasauskas AA, Morrow RL, Brown J, Morrow KA. BMPR2 Knockdown Enhances Hyperproliferative Phenotype of Pulmonary Endothelium. Society of Hospital Medicine, Wiregrass Chapter Annual Meeting. Dothan, Alabama September 2018.

    ·        Shoham S, Dukes D, Morrow RL, Brown J, Morrow KA, Vasauskas AA. Altered Balance of FKBP51 and FKBP52 in BMPR2-deficient Pulmonary Artery Endothelial Cells May Influence Cellular Phenotype and Migration. Society of Hospital Medicine, Wiregrass Chapter Annual Meeting. Dothan, Alabama September 2018.

    ·        Decker EP, Vasauskas AA, Morrow RL, Morrow KA, Brown J. FKBP51 Regulates Proliferation and TGFβ Production in Pulmonary Microvascular Cells. Society of Hospital Medicine, Wiregrass Chapter Annual Meeting. Dothan, Alabama September 2018.

    ·        Vasauskas AA, Robinson A, and Morrow RL. Early introduction of self-care techniques and their perceived benefit to medical students. International Association of Medical Science Educators. Las Vegas, NV, June 2018 (Presenter).

    ·        Brown JR, Morrow R, Morrow KA, Vasauskas AA. FK506 binding Protein 51 Plays a Role in Pulmonary Endothelial Cell Phenotype Switching Experimental Biology. San Diego CA, April 2018 (Presenter).

    ·        Josephs CA, Ceballos R, Vasauskas AA, Morrow RL, Morrow KA. Loss of BMPR2 Confers Proliferative Advantage on Pulmonary Artery Endothelial Cells by Decreasing Dependence on Growth Suppressor Merlin. Experimental Biology. San Diego, CA, April 2018.

    ·        Vasauskas AA, Buchman M, and Richardson CL. Health and Anatomy in the Wiregrass: a unique workshop for high school students in the Southeast region combining physiology, anatomy, scientific research, and creative thought. Experimental Biology. San Diego CA, April 2018 (Presenter).

    ·        Josephs CA, Ceballos R, Vasauskas AA, Morrow RL, Morrow KA. Loss of BMPR2 Leads to Decreased Dependence on Merlin in Pulmonary Artery Endothelial Cells as a Mechanism of Growth Suppression. Experimental Biology, San Diego CA, April 2018.

    ·        Brown V, Graziano L, Morrow R, Morrow KA, and Vasauskas AA. Characterization of bone morphogenic protein II-deficient pulmonary artery endothelial cells. Medical Association of the State of Alabama. Montgomery, AL, April 2018. (FIRST PLACE, Research Poster Presentation).

    ·        Graziano LA, Brown VR, Kalathuru S, Vasauskas AA. Characterization of bone morphogenic protein II-deficient pulmonary artery and pulmonary microvascular endothelial cells. American Medical Student Association. Washington DC, March 2018.

    ·        Brown V, Vasauskas AA, Morrow RL, Morrow KA, and Brown JR. Lipopolysaccharide differentially regulates occluding expression in pulmonary artery and microvascular endothelial cells. Alabama Osteopathic Medical Association. Destin, FL, July 2017. (FIRST PLACE, Research Poster Presentation).

    ·        Vasauskas AA, Richardson CL, Anderson SA, and Robinson AL. Educating the educators: a unique physiology- and anatomy-based educator workshop in the Wiregrass region. Experimental Biology.  Chicago, IL, 2017. (Presenter).

    ·        Vasauskas AA.  Perceived benefit of yoga practice on medical school student well-being. International Association of Medical Science Educators. Burlington, VT, 2017. (Presenter).

    ·        Richardson C, Vasauskas A, Robinson A, and Anderson S.  Increasing awareness and practical application of anatomical and physiological science in high school students. International Association of Medical Science Educators. Burlington, VT, June 2017.

    ·        Vasauskas AA and Cioffi DL.  Role of FKBP51 in Pulmonary Arterial Hypertension.  Experimental Biology. Boston, MA, March 2015.

    ·        Vasauskas AA, Patel P, Patel N, and Cioffi DL.  O-GlcNAcylation of STIM1 in pulmonary artery endothelial cells. Experimental Biology. San Diego, CA, April 2014. (Presenter).

    ·        Vasauskas AA and Cioffi DL.  Phosphorylation of TRPC4 as a possible regulatory mechanism of Isoc. Experimental Biology. Boston, MA, April 2013 (Presenter).

    ·        Vasauskas AA, Wang X, Chen H, Wu S, and Cioffi DL.  The serine-threonine calcium/calmodulin-activated phosphatase calcineurin is involved in regulation of store-operated calcium entry.  Experimental Biology. San Diego, CA, April 2012 (Presenter).

    ·        Vasauskas AA, Hubler TR, and Scammell..  Proximal and distal Egr-1 sites mediate GnRH-responsiveness of the squirrel monkey chorionic gonadotropin β-subunit promoter in LβT2 cells.  Experimental Biology. New Orleans, LA, April 2009 (Presenter).

    ·        Hubler TR, Vasauskas AA, Brackin LB, and Scammell JG.  Distinct promoter sequences mediate pituitary- and placenta-specific expression of squirrel monkey chorionic gonadotropin β-subunit.  Seattle Primate Genomics Conference.  Seattle, WA, April 2008 (Presenter).

    ·        Ghanbari, H.A., Vasauskas, A.A., Bensmail, I., Lebowitz, M.L.  HAAH is a serum biomarker for prostate cancer.  AACR International Conference on Molecular Diagnostics in Cancer Therapeutic Development. Chicago, IL 2006.

    ·        Vasauskas A.A., Glass, L., Ghanbari K., Lebowitz, M.L., Rani, C., Maric M., and Ghanbari, H.A.  HAAH as a Biomarker for Pancreatic Adenocarcinoma using IHC, qRT RCR and ELISA.  AACR—Molecular Targets and Cancer Therapeutics Meeting.  Boston, MA, November 2003 (Presenter).

    ·        Finney, A.H., Lebowitz, M.L., Vasauskas, A.A., Ghanbari, K., Nelson, V.M., and Ghanbari, H.A.  Antiproliferative and Anti-Metastatic Activities of Monoclonal Antibodies to Human Aspartyl (asapaginyl) β-hydroxylase.  AACR—Molecular Targets and Cancer Therapeutics Meeting.  Boston, MA, November 2003.

    ·        Audrey A. Vasauskas,  Cyra M. Ranji, Kasra Ghanbari, Michael S. Lebowitz, and Hossein A. Ghanbari.  Human Aspartyl (Asparaginyl) -Hydroxylase is a Serum Biomarker of Breast, Ovarian, and Prostate Cancer.  American Association of Cancer Research. Washington DC, July 2003.

    ·        M.S. Lebowitz, A.H. Finney, V.M. Nelson, A.A. Vasauskas, K. Ghanbari, A.H. Deutch, and H.A. Ghanbari. Inhibition of Cancer Cell Proliferation, Motility and Invasiveness by Monoclonal Antibodies for Human Aspartyl (Asparaginyl) β-Hydroxylase (HAAH).  American Academy of Cancer Research. Miami, FL, 2001

    ·        Beheshti, I., Ghanbari, K., Vasauskas, AA, Ghanbari, H  Urinary AD7C-NTP as a Peripheral Marker for Alzheimer’s Disease. American Association of Clinical Chemists. New Orleans, LA, July 1999

    ·        Ghanbari HA, Ghanbari K, Vasauskas AA, Munzar MR. Comparison of Urinary AD7C-NTP Levels in Alzheimer’s Disease With Normal and Neurological Psychiatric Controls: Diagnostic Value of AD7C-NTP as Diagnostic Marker. American Academy of Neurology.Toronto, Ontario, Canada, April 1999

    ·        Ghanbari HA, Ghanbari K, Vasauskas A, Mattero A, and Munzar M. Urinary AD7C-NTP as a Marker for Alzheimer’s Disease.  American Psychiatric Association. Washington, D.C., May 1999

    Funded research support

    Center for Nutrition Studies, T. Colin Campbell Institute (8/2022-7/2023)

    Food as Medicine: Dig with our Future Docs

    Role: PI

    $2,200

     

    SE Health Foundation (05/2022 – 04/2023)

    ACOM Summer Research Program

    Role: PI/Research Chair

    $27,000

     

    Alabama College of Osteopathic Medicine Intramural Research Grant (06/2017 - 2023)

    Role of FKBP51 in pulmonary arterial hypertension

    The goal of this study is to determine whether upregulation of FKBP51 contributes to pulmonary arterial hypertension

    Role: co-PI

    $40,000/year

     

    American Medical Association (6/2021 – 12/2022)

    Assessment of the AMA blood pressure modules throughout a medical school curriculum

    Role: co-PI/Team member

    $20,000

     

    1R15HL137135-01A1 (06/01/2018 – 05/31/2022)

    National Heart, Lung, and Blood Institute

    Role of FKBP51 in pulmonary arterial hypertension

    The goal of this study is to determine whether upregulation of FKBP51 contributes to pulmonary arterial hypertension

    Role: PI

    $277,277

     

    5UG4LM012340-05 subaward 1600679 (05/01/2020 – 04/30/2021)

    National Institutes of Health

    National Network of Libraries of Medicine (NNLM)

    Southeastern/Atlantic Regional Medical Library

    Subaward title: TEACH across Alabama

    Role: co-PI

    $11,593

     

    5F32HL112565-02 (2011-2013)

    National Heart, Lung, and Blood Institute

    Role of calcineurin in store-operated calcium entry of pulmonary endothelium

    The goal of this study was to determine whether calcineurin was a regulator of the store-operated Isoc channel in pulmonary artery endothelial cells.

    Role: PI

    $104,000

     

    17AIREA33680155 (07/01/2017 – 05/30/2018)

    American Heart Association

    Role of FKBP51 in pulmonary arterial hypertension

    The goal of this study is to determine whether upregulation of FKBP51 contributes to pulmonary arterial hypertension

    Role: PI

    $77,000

     

    SE Health Foundation (05/2021 – 04/2022)

    ACOM Summer Research Program

    Role: PI/Research Chair

    $29,500

     

    SE Health Foundation (05/2020 – 04/2021)

    ACOM Summer Research Program

    Role: PI/Research Chair

    $24,500

     

    SE Health Foundation (03/2021 – 06/ 2021)

    ACOM Food as Medicine Nutrition Curricular event

    $1,600


  • White

    Research Interests

    • Public awareness of pandemic health policies and how they are created
    • Over-the-counter cold medicine usage patterns
    • Effect of voluntary respiratory pattern changes on blood biochemistry and cardiac rhythm

    PUBLICATIONS

    • Kadavakollu S, Kumar R, Aradhyula L et al. Ten practical tips for integration of biochemistry topics into systems-based medical school curriculum [version 1; peer review: 1 approved, 1 approved with reservations]. MedEdPublish 2023, 13:23 (https://doi.org/10.12688/mep.19633.1)
    • Inhibition of CYP2S1 mediated metabolism of anticancer prodrug AQ4N by liarozole. Naveen K.M. Singh, Shawn R. White, Sudhakar Kalagara, and Samuel Kadavakollu. Journal of Applied Pharmaceutical Science. 2017, 7(2), 1-9.
    • Bradykinin in Hemipepsis ustulata: A novel method for safely milking wasps. Shawn R. White and Samuel Kadavakollu. Toxicon. 2016, 117, 49-52.
    • Translational Fidelity Mediated Regulation of ER-Stress by Dph3. Samuel Kadavakollu, Shawn R. White, Arthi Chandran, Kiran K. Andra, Naveen K.M. Singh and Rahul Vemula. Journal of Biomedical Sciences. 2015, 5(1), 19.
    • Determination of Fatty Acid Profiles of Commercially Available Cooking Oils by Acid-Catalyzed Transesterification. Shawn R. White, James Sanders, Carol Kay Lindsay, Catherine Stailey, and Samuel Kadavakollu. Journal of Undergraduate Chemistry Research. 2015, 14(1), 35-37.
    • Clotrimazole as a Cancer Drug: A Short Review. Samuel Kadavakollu, Catherine Stailey, Shekar Kunapareddy, and Shawn White. Medicinal Chemistry. 2014, 4(11), 722.
    • Regarding Claims of Improved Efficiency in Internal Combustion Gasoline Engines by the Addition of Hydrogen and Oxygen Gas Mixtures. Paul Hanson and Shawn White. Journal of Undergraduate Chemistry Research. 2013, 12(1), 19.
    • Sceloporus jarrovii (Yarrow’s Spiny Lizard) Range Extension. Shawn R. White, Randy D. Jennings, Douglas E. Ruby, and George A. Middendorf. Herpetological Review. 2010, 41(1), 108.

  • Amenu Wirtu Web 2024

    Research Interests: Neuroinflammation and Aging-Related Neurodegenerative Diseases: Anatomical Trends, Variations, and Educational Perspectives; Clinical Case Scenarios, Imaging and Diagnostics in Vulnerable Communities; Methods & Innovations/AI-driven Models and Practices. 

    Scholarly Activities/Publications

    • Geneti, S. A., & Wirtu, A. T. (2024). Communicating Neuroanatomical Fibers in Health and Diseases. Journal of Human Anatomy, 8(1), 000205.
    • Eshetu, M. A., Goshu, D. Y., Kebede, M. A., Negate, H. M., Habtezghi, A. B., Gregory, P. M., Wirtu, A. T., & Gemechu, J. M. (2024). Patterns and Complications of Congenital Heart Disease in Adolescents and Adults in Ethiopia. Journal of Cardiovascular Development and Disease, 11(8), 253.
    • Kebede, M. A., Mengistu, Y. T., Loge, B. Y., Eshetu, M. A., Shash, E. P., Wirtu, A. T., & Gemechu, J. M. (2024). Determinants of Disease Progression in Autosomal Dominant Polycystic Kidney Disease. Journal of Personalized Medicine, 14(9), 936.
    • Wirtu, A. T., & Manjatika, A. T. (2024). Challenges in Sourcing Bodies for Anatomy Education and Research in Ethiopia: Pre- and Post-COVID-19 Scenarios. Annals of Anatomy, 254, 152234.
    • Kebede, M. A., Wirtu, A. T., Mekonnen, B. E., Tilahun, A. G., Degaga, T. K., & Gemechu, J. M. (2023). Clinical Stroke Validation Methods in Under-Resourced Ethiopian Hospital Settings. Journal of Academic Development and Education, Anatomical Sciences Special Edition. ISSN 2051-359.
    • Wirtu, A. T. (2021). Diabetics-Related Foot Deformity: Prevalence, Risk Factors, Knowledge, and Practice. Trends in Anatomy and Physiology, 23.
    • Wirtu, A. T. (2021). Diagnosis of Pregnant Women with Seizures at Tikur Anbessa Hospital. Journal of Diagnosis & Case Reports, SRC/JDCRS, 2-6.
    • Wubale, Y., & Wirtu, A. T. (2016). Placenta in Preeclamptic and Gestational Diabetes Mellitus Mothers: A Macroarchitectural Study at Gandhi and Black Lion Hospitals, Addis Ababa, Ethiopia. Addis Ababa University, 10.
    • Kebede, B. E., Geleta, M. A., & Wirtu, A. T. (2021). Diagnosis of Pregnant Women with Seizures. Journal of Diagnosis, 12-15.
    • Wirtu, A. T. (2015). Orexin in Inflammation and Aging-Related Neurodegenerative Diseases.
    • Colavito, V., Tesoriero, C., Wirtu, A. T., Grassi-Zucconi, G., & Bentivoglio, M. (2015). Limbic Thalamus and State-Dependent Behavior: The Paraventricular Nucleus of the Thalamic Midline as a Node in Circadian Timing and Sleep/Wake-Regulatory Networks. Neuroscience & Biobehavioral Reviews, 54, 3-17.
    • Bentivoglio, M., & Wirtu, A. T. (2014). Orexinergic Neurons in a Murine Model of Alzheimer’s Disease. IRIS Verona, 2(1), 143.
    • Bentivoglio, M., Colavito, V., Rodriguez, A., Gemechu, J. M., Wirtu, A. T., Del Percio, C., Messano, F., Babiloni, C., Dix, S., Richardson, J. C., & Bertini, G. (2014). Sleep/Wake Changes and Loss of Orexinergic Neurons in Transgenic Mouse Models of Alzheimer’s Disease. Journal of Sleep Research, 309.
    • Degaga, T. K., Zenebe, A. M., Wirtu, A. T., Woldehawariat, T. D., Dellie, S. T., & Gemechu, J. M. (2020). Anatomographic Variants of the Sphenoid Sinus in the Ethiopian Population. Diagnostics, 10.
    • Geneti, S. A., Wirtu, A. T., & Hailegiorgis, S. T. (2018). Variations in Distal Attachment of Muscles of the Leg, Foot, and Hand and Their Clinical Implications in the Population of Central Ethiopia. Italian Journal of Anatomy and Embryology, 123, 165-172.
    • Wirtu, A. T., Geneti, S. A., Zenebe, A. M., Ewnetu, S. A., & Gemechu, J. M. (2018). Incidence of Persistent Metopic Suture and Extra Sacral Foramina in the Ethiopian Population. Italian Journal of Anatomy and Embryology, 123, 108-113.
    • Gemechu, J. M., Geneti, S. A., Zenebe, A. M., Ewnetu, S. A., & Wirtu, A. T. (2017). Persistent Metopic Suture and Extra Sacral Foramina: Clinically Significant Anatomical Variants. The FASEB Journal, 31.
    • Wirtu, A. T., Geneti, S. A., Haile Georgis, S. T., & Gemechu, J. M. (2017). Neuroanatomical Variants of Clinical Importance in the Ethiopian Population. The FASEB Journal, 31.
    • Savchenko, J. I., Wilson, S. K., Eutushenko, E. G., Azeez, I. A., Olopade, F. E., Laperchia, C., Andrioli, A., Wirtu, A. T., Onwuka, S. K., Bentivoglio, M., & Olopade, J. O. (2016). Abstracts Presented at the 12th Conference of the Neuroscience Society of Nigeria.
    • Bertini, G., Colavito, V., Wirtu, A. T., & Bentivoglio, M. (2014). Orexinergic Neuron Susceptibility to Neuroinflammatory and Aging-Related Neurodegenerative Diseases. Italian Journal of Anatomy and Embryology, 119, 17.
    • Rodriguez, J. C. R., Colavito, V., Gemechu, J. M., & Wirtu, A. T. (2014). Time-Course of Cortical Activity Alterations and Aβ Deposition in Transgenic Mouse Models of Alzheimer’s Disease. IRIS Verona, 1(1), 146.
    • Wirtu, A. T. (M.Sc. Thesis). The Effects of Ricinus Communis and Jatropha Curcas Seed Aqueous Extracts on the Histology of the Uterus and Ovary in Mice. HDL, 1, 105.
    • Wirtu, A. T. (Thesis). Anti-Fertility Property of Artemisia Afra and Leonotis Ocymifolia in Mice. HDL, 1, 75

    Projects & Grants

    •  Pharma Cog project under the EC 7th Framework Programme for IMI (Grant Agreement No. 115009) from 2013 to 2015.
    • World Bank Ebola Emergency Response Project (EERP #IDA) Consulting Services for Pre-Clinical Faculty from 2017 to 2022.
    • USAID Bridge-U Project in collaboration with the College of Health Sciences, Yale University, Vanderbilt University and the University of Liberia from 2023 to 2024.

    Recent Presentations at International Conferences/Associations

    • Speaker & Exhibitor (March 24, 2023, Washington D.C.): Anatomy Connected 2023 - An Insight into the Wirtu Model of Interactive Medical Education Platform.
    • Presenter & Speaker (August 5, 2022, IFAA 2022, Turkey): Body Sourcing for Anatomical Education and Research: Experiences from the African Continent – Symposium chaired by Goran Štrkalj & Brendon Billings.
    • Presenter & Speaker (June 5, 2022, IAMSE 2022 Conference): Mitigating Implicit Bias in Medical Curriculum – Panel discussion with Jacqueline Powell, Jayne Reuben, Zaki Sherif, Tameka Clemons, Robert Copeland, Ian Murray, and Amenu Tolera Wirtu.

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